재발한 유육종증의 골수 침범 증례 보고Bone Marrow Involvement in Relapsed Sarcoidosis: A Case Report
- Other Titles
- Bone Marrow Involvement in Relapsed Sarcoidosis: A Case Report
- Authors
- 이정민
- Issue Date
- Jul-2021
- Publisher
- 대한진단검사의학회
- Keywords
- Bone marrow involvement; Chronic granulomatous diseases; Diagnostic tests; Cytopenia; Extrapulmonary sarcoidosis; Sarcoidosis
- Citation
- Laboratory Medicine Online, v.11, no.3, pp 194 - 198
- Pages
- 5
- Indexed
- KCI
- Journal Title
- Laboratory Medicine Online
- Volume
- 11
- Number
- 3
- Start Page
- 194
- End Page
- 198
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/54417
- DOI
- 10.47429/lmo.2021.11.3.194
- ISSN
- 2093-6338
2093-6338
- Abstract
- Sarcoidosis can involve multiple organs and is characterized by non-caseating granuloma on biopsy, which is not pathognomonic of this disease. Therefore, diagnosis requires exclusion of other causes of granuloma, including malignant neoplasm, infections, autoimmune diseases, drug exposure, environmental causes, lymphoma, and tuberculosis. Herein, we present a rare case of a patient with a primary manifestation of sarcoidosis, with typical bilateral hilar adenopathy, and recurrence in the bone marrow. A 50-year-old female patient, who had been diagnosed with sarcoidosis at age 38, was admitted for petechia on both legs and pancytopenia. The patient was concluded to be “highly probable” for sarcoidosis, with at least 90% likelihood, according to the World Association of Sarcoidosis and Other Granulomatous Diseases (WASOG) organ assessment instrument. Moreover, the patient had a bone marrow biopsy positive for granulomatous inflammation. Hence, all findings supported the diagnosis of sarcoidosis. Because sarcoidosis is difficult to definitively diagnose, it will be useful to better understand the application, interpretation, and limitations of the WASOG instrument for bone marrow involvement assessment.
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Collections - 5. Others > Others(Medicine) > 1. Journal Articles
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