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Effect of histological examination on the diagnosis of pancreatic mass using endoscopic ultrasound fine-needle aspiration

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dc.contributor.authorChoi, Seong Ji-
dc.contributor.authorLee, Jae Min-
dc.contributor.authorLee, Kang Won-
dc.contributor.authorChoi, Hyuk Soon-
dc.contributor.authorKim, Eun Sun-
dc.contributor.authorKeum, Bora-
dc.contributor.authorYoon, Jai Hoon-
dc.contributor.authorJeen, Yoon Tae-
dc.contributor.authorChun, Hoon Jai-
dc.contributor.authorLee, Hong Sik-
dc.contributor.authorChoi, Ho Soon-
dc.date.accessioned2021-10-25T08:40:16Z-
dc.date.available2021-10-25T08:40:16Z-
dc.date.created2021-10-25-
dc.date.issued2021-09-
dc.identifier.issn1899-5276-
dc.identifier.urihttps://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/54594-
dc.description.abstractBackground. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a well-established method for the diagnosis of solid pancreatic lesions. However, the diagnostic yield of EUS-FNA for pancreatic lesions varies at around 70-90%. Samples from EUS-FNA consist of cells and tissues that can be analyzed separately, and the results can be combined for a final diagnosis. Objectives. To investigate the effect of cytological and histological analysis of EUS-FNA samples on the final diagnosis, and identify factors that may affect the accuracy of the cytological, histological, and overall analysis. Materials and methods. A single-center prospective observational study was conducted at a tertiary university hospital from July 2018 to June 2019. Patients who underwent EUS-FNA for pancreatic solid lesions with a 22-gauge EUS-FNA needle were included in our study. Liquid-based cytological analysis of the speci-men and histological analysis of the whitish core were performed, and factors that affected the diagnostic accuracy of each analysis were evaluated. Results. In 63 EUS-FNA samples, the overall diagnostic accuracy was 87.3%, which was significantly higher than the cytological accuracy of 73.8% (p = 0.031) and the histological accuracy of 69.8% (p = 0.001). Factors that affected the results differed in each group: 1) cytological analysis: size, location, and approach method; 2) histological analysis: specimen weight; and 3) overall analysis: size, location, and approach method. Conclusions. Histologic evaluation of core material obtained from EUS-FNA improved diagnostic accuracy, and factors that affected each result were analyzed. Further studies with prospective randomized trials are recommended to support our data.-
dc.language영어-
dc.language.isoen-
dc.publisherAkademia Medyczna we Wroclawiu/Wroclaw Medical University-
dc.titleEffect of histological examination on the diagnosis of pancreatic mass using endoscopic ultrasound fine-needle aspiration-
dc.typeArticle-
dc.contributor.affiliatedAuthorLee, Jae Min-
dc.contributor.affiliatedAuthorLee, Kang Won-
dc.contributor.affiliatedAuthorChoi, Hyuk Soon-
dc.contributor.affiliatedAuthorKim, Eun Sun-
dc.contributor.affiliatedAuthorKeum, Bora-
dc.contributor.affiliatedAuthorJeen, Yoon Tae-
dc.contributor.affiliatedAuthorChun, Hoon Jai-
dc.contributor.affiliatedAuthorLee, Hong Sik-
dc.identifier.doi10.17219/acem/136278-
dc.identifier.scopusid2-s2.0-85114004847-
dc.identifier.wosid000704583000002-
dc.identifier.bibliographicCitationAdvances in Clinical and Experimental Medicine, v.30, no.9, pp.885 - 891-
dc.relation.isPartOfAdvances in Clinical and Experimental Medicine-
dc.citation.titleAdvances in Clinical and Experimental Medicine-
dc.citation.volume30-
dc.citation.number9-
dc.citation.startPage885-
dc.citation.endPage891-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaResearch & Experimental Medicine-
dc.relation.journalWebOfScienceCategoryMedicine, Research & Experimental-
dc.subject.keywordPlusEUS-GUIDED FNA-
dc.subject.keywordPlusBIOPSY-
dc.subject.keywordPlusLESIONS-
dc.subject.keywordPlusYIELD-
dc.subject.keywordPlusULTRASONOGRAPHY-
dc.subject.keywordPlusMETAANALYSIS-
dc.subject.keywordPlusIMPROVE-
dc.subject.keywordAuthorendosonography-
dc.subject.keywordAuthordiagnosis-
dc.subject.keywordAuthorpancreatic neoplasms-
dc.subject.keywordAuthorendoscopic ultrasound-guided fine-needle aspiration-
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Choi, Hyuk Soon
Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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