Human immunodeficiency virus (HIV) and hepatitis virus coinfection among HIV-infected Korean patients: The Korea HIV/AIDS cohort studyopen access
- Authors
- Kim Y.C.; Ahn J.Y.; Kim J.M.; Kim Y.J.; Park D.W.; Yoon Y.K.; Song J.Y.; Kim S.W.; Lee J.S.; Choi B.Y.; Choi Y.S.; Choi J.-Y.; Han M.G.; Kang C.; Choi J.Y.
- Issue Date
- 2017
- Publisher
- Korean Society for Chemotherapy
- Keywords
- Coinfection; Hepatitis B virus; Hepatitis C virus; HIV infection
- Citation
- Infection and Chemotherapy, v.49, no.4, pp 268 - 274
- Pages
- 7
- Indexed
- SCOPUS
ESCI
KCI
- Journal Title
- Infection and Chemotherapy
- Volume
- 49
- Number
- 4
- Start Page
- 268
- End Page
- 274
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/5607
- DOI
- 10.3947/ic.2017.49.4.268
- ISSN
- 2093-2340
2092-6448
- Abstract
- Background: Despite declines in mortality and morbidity rates of patients with human immunodeficiency virus (HIV) infection as the result of highly active antiretroviral therapy, liver diseases due to chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are a leading cause of death among HIV-infected patients. However, HIV and HBV or HCV coinfection is still poorly documented, and more information is needed to better understand the characteristics of HIV-infected patients in Korea. Materials and Methods: A cross-sectional study was performed to investigate clinical characteristics and prevalence of HBV and HCV infection in HIV patients enrolled in the Korea HIV/acquired immune deficiency syndrome (AIDS) cohort study from 17 institutions between December 2006 and July 2013. Results: Among the 1,218 HIV-infected participants, 541 were included in this study. The prevalence of HBV-HIV and HCV-HIV coinfection was 5.0% (27/541) and 1.7% (9/541), respectively. There was no patient who was positive for both HBs antigen and HCV antibody. In multivariate logistic regression analysis, HBV unvaccinated status was a significant risk factor for HBV-HIV coinfection (odds ratio = 4.95, 95% confidence interval = 1.43-17.13). Conclusion: HBV and HCV infection was more common in HIV-infected persons enrolled in the Korean HIV/AIDS cohort, than in the general population in Korea. © 2017 by The Korean Society of Infectious Diseases.
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Collections - 2. Clinical Science > Department of Infectious Diseases > 1. Journal Articles
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