Clinical Practice Guidelines for the Management of Atypical Hemolytic Uremic Syndrome in Koreaopen access
- Authors
- Cheong, Hae Il; Jo, Sang Kyung; Yoon, Sung-Soo; Cho, Heeyeon; Kim, Jin Seok; Kim, Young Ok; Koo, Ja-Ryong; Park, Yong; Park, Young Seo; Shin, Jae Il; Yoo, Kee Hwan; Oh, Doyeun
- Issue Date
- Oct-2016
- Publisher
- KOREAN ACAD MEDICAL SCIENCES
- Keywords
- Guidelines; Diagnosis; Treatment; Atypical Hemolytic Uremic Syndrome
- Citation
- JOURNAL OF KOREAN MEDICAL SCIENCE, v.31, no.10, pp 1516 - 1528
- Pages
- 13
- Indexed
- SCI
SCIE
SCOPUS
KCI
- Journal Title
- JOURNAL OF KOREAN MEDICAL SCIENCE
- Volume
- 31
- Number
- 10
- Start Page
- 1516
- End Page
- 1528
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/6016
- DOI
- 10.3346/jkms.2016.31.10.1516
- ISSN
- 1011-8934
1598-6357
- Abstract
- Atypical hemolytic uremic syndrome (aHUS) is a rare syndrome characterized by micro-angiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. The major pathogenesis of aHUS involves dysregulation of the complement system. Eculizumab, which blocks complement C5 activation, has recently been proven as an effective agent. Delayed diagnosis and treatment of aHUS can cause death or end-stage renal disease. Therefore, a diagnosis that differentiates aHUS from other forms of thrombotic microangiopathy is very important for appropriate management. These guidelines aim to offer recommendations for the diagnosis and treatment of patients with aHUS in Korea. The guidelines have largely been adopted from the current guidelines due to the lack of evidence concerning the Korean population.
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- Appears in
Collections - 2. Clinical Science > Department of Pediatrics > 1. Journal Articles
- 2. Clinical Science > Department of Medical Oncology and Hematology > 1. Journal Articles
- 2. Clinical Science > Department of Nephrology and Hypertension > 1. Journal Articles
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