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Cited 10 time in webofscience Cited 9 time in scopus
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A Randomized Controlled Trial of Compression Rates during Cardiopulmonary Resuscitation

Authors
Hwang, Sung OhCha, Kyoung-ChulKim, KyuseokJo, You HwanChung, Sung PhilYou, Je SungShin, JonghwanLee, Hui JaiPark, Yoo SeokKim, SeunghwanChoi, Sang-cheonPark, Eun-JungKim, Won YoungSeo, Dong-WooMoon, SungwooHan, GapsuChoi, Han SungKang, HyunggooPark, Seung MinKwon, Woon YongChoi, Eunhee
Issue Date
Sep-2016
Publisher
대한의학회
Keywords
Cardiopulmonary Resuscitation; Cardiac Arrest; Basic Life Support
Citation
Journal of Korean Medical Science, v.31, no.9, pp 1491 - 1498
Pages
8
Indexed
SCI
SCIE
SCOPUS
KCI
Journal Title
Journal of Korean Medical Science
Volume
31
Number
9
Start Page
1491
End Page
1498
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/6120
DOI
10.3346/jkms.2016.31.9.1491
ISSN
1011-8934
1598-6357
Abstract
The objective of this study was to compare the efficacy of cardiopulmonary resuscitation (CPR) with 120 compressions per minute (CPM) to CPR with 100 CPM in patients with nontraumatic out-of-hospital cardiac arrest. We randomly assigned patients with nontraumatic out-of-hospital cardiac arrest into two groups upon arrival to the emergency department (ED). The patients received manual CPR either with 100 CPM (CPR-100 group) or 120 CPM (CPR-120 group). The primary outcome measure was sustained restoration of spontaneous circulation (ROSC). The secondary outcome measures were survival discharge from the hospital, one-month survival, and one-month survival with good functional status. Of 470 patients with cardiac arrest, 136 patients in the CPR-100 group and 156 patients in the CPR-120 group were included in the final analysis. A total of 69 patients (50.7%) in the CPR-100 group and 67 patients (42.9%) in the CPR-120 group had ROSC (absolute difference, 7.8% points; 95% confidence interval [CI], -3.7 to 19.2%; P = 0.183). The rates of survival discharge from the hospital, one-month survival, and one-month survival with good functional status were not different between the two groups (16.9% vs. 12.8%, P = 0.325; 12.5% vs. 6.4%, P = 0.073; 5.9% vs. 2.6%, P = 0.154, respectively). We did not find differences in the resuscitation outcomes between those who received CPR with 100 CPM and those with 120 CPM. However, a large trial is warranted, with adequate power to confirm a statistically non-significant trend toward superiority of CPR with 100 CPM. Trial Registration Clinical Research Information Service Identifier: KCT0000231
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Anam Hospital (Department of Emergency Medicine, Anam Hospital)
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