Gastric lesions in patients with Crohn's disease in Korea: A multicenter study
DC Field | Value | Language |
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dc.contributor.author | So H. | - |
dc.contributor.author | Ye B.D. | - |
dc.contributor.author | Park Y.S. | - |
dc.contributor.author | Kim J. | - |
dc.contributor.author | Kim J.S. | - |
dc.contributor.author | Moon W. | - |
dc.contributor.author | Lee K.-M. | - |
dc.contributor.author | Kim Y.S. | - |
dc.contributor.author | Keum B. | - |
dc.contributor.author | Kim S.-E. | - |
dc.contributor.author | Kim K.O. | - |
dc.contributor.author | Kim E.S. | - |
dc.contributor.author | Lee C.K. | - |
dc.contributor.author | Hong S.P. | - |
dc.contributor.author | Im J.P. | - |
dc.contributor.author | Koo J.S. | - |
dc.contributor.author | Choi C.H. | - |
dc.contributor.author | Shin J.E. | - |
dc.contributor.author | Lee B.I. | - |
dc.contributor.author | Huh K.C. | - |
dc.contributor.author | Kim Y.-H. | - |
dc.contributor.author | Kim H.-S. | - |
dc.contributor.author | Park Y.S. | - |
dc.contributor.author | Han D.S. | - |
dc.contributor.author | Korean Association for the Study of Intestinal Diseases | - |
dc.date.available | 2020-11-02T14:29:15Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1598-9100 | - |
dc.identifier.issn | 2288-1956 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/7059 | - |
dc.description.abstract | Background/Aims: Gastric pathology and Helicobacter pylori (H. pylori ) infection among Asian patients with Crohn's disease (CD) are still unclear. We evaluated gastric histologic features and frequency of H. pylori infection in Korean patients with CD. Methods: Among 492 patients with CD receiving upper gastrointestinal (GI) endoscopic evaluation in 19 Korean hospitals, we evaluated the endoscopic findings and gastric histopathologic features of 47 patients for our study. Histopathologic classification was performed using gastric biopsy tissues, and H. pylori infection was determined using the rapid urease test and histology. Results: There were 36 men (76.6%), and the median age of patients at the time of upper GI endoscopy was 23.8 years (range, 14.2-60.5). For CD phenotype, ileocolonic disease was observed in 38 patients (80.9%), and non-stricturing, nonpenetrating disease in 31 patients (66.0%). Twenty-eight patients (59.6%) complained of upper GI symptoms. Erosive gastritis was the most common gross gastric feature (66.0%). Histopathologically, H. pylori -negative chronic active gastritis (38.3%) was the most frequent finding. H. pylori testing was positive in 11 patients (23.4%), and gastric noncaseating granulomata were detected in 4 patients (8.5%). Gastric noncaseating granuloma showed a statistically significant association with perianal abscess/ fistula (P =0.0496). Conclusions: H. pylori -negative chronic active gastritis appears to be frequent among Korean patients with CD. The frequency of H. pylori infection was comparable with previous studies. An association with perianal complications suggests a prognostic value for gastric noncaseating granuloma in patients with CD. © 2016. Korean Association for the Study of Intestinal Diseases. All rights reserved. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Korean Association for the Study of Intestinal Diseases | - |
dc.title | Gastric lesions in patients with Crohn's disease in Korea: A multicenter study | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.5217/ir.2016.14.1.60 | - |
dc.identifier.scopusid | 2-s2.0-84978278120 | - |
dc.identifier.bibliographicCitation | Intestinal Research, v.14, no.1, pp 60 - 68 | - |
dc.citation.title | Intestinal Research | - |
dc.citation.volume | 14 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 60 | - |
dc.citation.endPage | 68 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002076195 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | Crohn disease | - |
dc.subject.keywordAuthor | Gastritis | - |
dc.subject.keywordAuthor | Granuloma | - |
dc.subject.keywordAuthor | Helicobacter pylori | - |
dc.subject.keywordAuthor | Stomach | - |
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