Relationship between menstrual irregularity and dyslipidemia in Korean women

Abstract

Background: Menstrual irregularity is known to be related to insulin resistance and cardiovascular risk factors. The aim of this study was to investigate the association between menstrual irregularity and dyslipidemia in Korean women.

Methods: Weanalyzedthe data of 3774 subjects from the Korean National Health and Nutrition Examination SurveyVconducted from2010 to 2012. The subjects were asked about menstrual irregularity throughself-reported questionnaire. The relationship of menstrual irregularity with dyslipidemia was assessed by using multivariable logistic regression analysis.

Results: In the menstrual irregularity group, the prevalence of dyslipidemia parameters such as hypercholesterolemia,hypo-high-density lipoproteincholesterolemia,and hyperlow- density lipoproteincholesterolemia were significantly higher thanin the normocyclic group.In particular, the risks of hypercholesterolemia and hypo-high-density lipoproteincholesterolemia were positively associated with menstrual irregularity after adjustingfor possible confounding variables.

Conclusion: Menstrual irregularity is associated with the prevalence of dyslipidemia and the increasing risk of dyslipidemia in Korean women.