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Cited 7 time in webofscience Cited 6 time in scopus
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Predictors of the patency of self-expandable metallic stents in malignant gastroduodenal obstruction

Authors
Kim, Seung HanChun, Hoon JaiYoo, In KyungLee, Jae MinNam, Seung JooChoi, Hyuk SoonKim, Eun SunKeum, BoraSeo, Yeon SeokJeen, Yoon TaeLee, Hong SikUm, Soon HoKim, Chang Duck
Issue Date
Aug-2015
Publisher
BAISHIDENG PUBLISHING GROUP INC
Keywords
Malignant gastroduodenal obstruction; Stent; Patency; Predictive factor; Carcinoembryonic antigen
Citation
WORLD JOURNAL OF GASTROENTEROLOGY, v.21, no.30, pp.9134 - 9141
Indexed
SCIE
SCOPUS
Journal Title
WORLD JOURNAL OF GASTROENTEROLOGY
Volume
21
Number
30
Start Page
9134
End Page
9141
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/7617
DOI
10.3748/wjg.v21.i30.9134
ISSN
1007-9327
Abstract
AIM: To investigate the predictive factors of self-expandable metallic stent patency after stent placement in patients with inoperable malignant gastroduodenal obstruction. METHODS: A total of 116 patients underwent stent placements for inoperable malignant gastroduodenal obstruction at a tertiary academic center. Clinical success was defined as acceptable decompression of the obstructive lesion within the malignant gastroduodenal neoplasm. We evaluated patient comorbidities and clinical statuses using the World Health Organization's scoring system and categorized patient responses to chemotherapy using the Response Evaluation Criteria in Solid Tumors criteria. We analyzed the relationships between possible predictive factors and stent patency. RESULTS: Self-expandable metallic stent placement was technically successful in all patients (100%), and the clinical success rate was 84.2%. In a multivariate Cox proportional hazards model, carcinoembryonic antigen (CEA) levels were correlated with a reduction in stent patency [P = 0.006; adjusted hazard ratio (aHR) = 2.92, 95% CI: 1.36-6.25]. Palliative chemotherapy was statistically associated with an increase in stent patency (P = 0.009; aHR = 0.27, 95% CI: 0.10-0.72). CONCLUSION: CEA levels can easily be measured at the time of stent placement and may help clinicians to predict stent patency and determine the appropriate stent procedure.
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5. Others > Others(Medicine) > 1. Journal Articles
2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

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Seo, Yeon Seok
Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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