Detailed Information

Cited 9 time in webofscience Cited 9 time in scopus
Metadata Downloads

The risk of perioperative adverse events in patients with chronic liver disease

Authors
Kim, Tae HyungUm, Soon HoYim, Sun YoungSeo, Yeon SeokYim, Hyung JoonJeen, Yoon TaeLee, Hong SikChun, Hoon JaeKim, Chang DuckAhn, HyongginLee, Yeji
Issue Date
Mar-2015
Publisher
WILEY
Keywords
cirrhosis; hepatitis; post-operative complication
Citation
LIVER INTERNATIONAL, v.35, no.3, pp.713 - 723
Indexed
SCIE
SCOPUS
Journal Title
LIVER INTERNATIONAL
Volume
35
Number
3
Start Page
713
End Page
723
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/8095
DOI
10.1111/liv.12529
ISSN
1478-3223
Abstract
Background & AimsChronic liver disease is a common comorbidity in surgery. To assess post-operative morbidity and mortality in relation to progression of chronic liver disease and to identify the risk factors. MethodsSix hundred and nine consecutive patients with chronic liver disease who underwent surgery were classified into two groups: non-cirrhotic (n=363) and cirrhotic (n=246). Randomly selected patients without underlying liver disease who underwent surgery were used as control group (n=148). ResultsThe occurrence of major post-operative complications was higher in the non-cirrhotic group than in the control group (11.8% vs. 6.1%, P=0.051); age, type of surgery and serum albumin level were independent predictors for post-operative morbidity. The frequency of significant post-operative liver damage (14.9% vs. 12.2%, P=0.920) and mortality (0.6% vs. 0.7%, P=0.871) did not differ between the two groups. The cirrhotic group had markedly higher incidences of post-operative mortality (10.2%), major complications (32.5%) and significant liver damage (43.1%) than the control and non-cirrhotic groups (all P<0.001). Type of surgery, Child-Pugh score and model for end-stage liver disease score were independently associated with post-operative morbidity and mortality in patients with cirrhosis. Specific data regarding post-operative morbidity and mortality were presented according to progression of liver disease and type of surgery. ConclusionNon-cirrhotic chronic liver diseases were associated with higher risk of post-operative morbidity, particularly in cases of major surgery, older age and hypoalbuminaemia. Cirrhosis further increased the risk, even death, depending on degree of hepatic decompensation and type of surgery.
Files in This Item
There are no files associated with this item.
Appears in
Collections
1. Basic Science > Department of Biostatistics > 1. Journal Articles
5. Others > Others(Medicine) > 1. Journal Articles
2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Kim, Chang Duck photo

Kim, Chang Duck
Others (Others(Others))
Read more

Altmetrics

Total Views & Downloads

BROWSE