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Cited 28 time in webofscience Cited 25 time in scopus
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A randomized, prospective trial on efficacy and tolerability of low-volume bowel preparation methods for colonoscopy

Authors
Yoo, In KyungLee, Jong SooChun, Hoon JaiJeen, Yoon TaeKeum, BoraKim, Eun SunChoi, Hyuk SoonLee, Jae MinKim, Seung HanNam, Seung JooKang, Hyo SungLee, Hong SikKim, Chang DuckUm, Soon HoSeo, Yeon SeokRyu, Ho Sang
Issue Date
Feb-2015
Publisher
ELSEVIER SCIENCE INC
Keywords
Polyethylene glycol with ascorbic acid; Sodium picosulfate
Citation
DIGESTIVE AND LIVER DISEASE, v.47, no.2, pp.131 - 137
Indexed
SCIE
SCOPUS
Journal Title
DIGESTIVE AND LIVER DISEASE
Volume
47
Number
2
Start Page
131
End Page
137
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/8193
DOI
10.1016/j.dld.2014.10.019
ISSN
1590-8658
Abstract
Background: Low-volume bowel preparations have been shown to provide an equivalent cleansing effect as that of a standard 4L polyethylene glycol. However, studies comparing the efficacy of low-volume bowel preparations are few, and the results have been controversial. This study aimed to compare the bowel cleansing quality and tolerability between sodium picosulfate/magnesium citrate and polyethylene glycol with ascorbic acid. Methods: A randomized study was performed with two hundred outpatients who were prospectively enrolled. The Boston Bowel Preparation Scale and the Aronchick scale were used to evaluate the bowel cleansing quality, and bubble scoring was also performed to back up both results. To investigate patients' preferences and tolerability, a questionnaire was administered. Results: Sodium picosulfate/magnesium citrate was not inferior to polyethylene glycol with ascorbic acid in terms of successful bowel preparation (>= 6 Boston scale score: 80% vs. 82%; p=0.718, adequate Aronchick grade: 93% vs. 96%; p=0.352). In addition, sodium picosulfate/magnesium citrate caused fewer gastrointestinal symptoms, and tasted better than polyethylene glycol with ascorbic acid. Conclusions: Sodium picosulfate/magnesium citrate was not inferior to polyethylene glycol with ascorbic acid in cleansing efficacy, and was found to have higher tolerability. (C) 2014 Published by Elsevier Ltd on behalf of Editrice Gastroenterologica Italiana S.r.l.
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2. Clinical Science > Department of Internal Medicine > 1. Journal Articles
5. Others > Others(Medicine) > 1. Journal Articles
2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

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