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Cited 37 time in webofscience Cited 37 time in scopus
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Prevalence of Uninvestigated Dyspepsia and Gastroesophageal Reflux Disease in Korea: A Population-Based Study Using the Rome III Criteria

Authors
Min, Byung-HoonHuh, Kyu ChanJung, Hye-KyungYoon, Young HoonChoi, Kee DonSong, Kyung HoKeum, BoraKim, Jung Won
Issue Date
Nov-2014
Publisher
SPRINGER
Keywords
Dyspepsia; Gastroesophageal reflux disease; Prevalence; Epidemiology
Citation
DIGESTIVE DISEASES AND SCIENCES, v.59, no.11, pp.2721 - 2729
Indexed
SCIE
SCOPUS
Journal Title
DIGESTIVE DISEASES AND SCIENCES
Volume
59
Number
11
Start Page
2721
End Page
2729
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/8810
DOI
10.1007/s10620-014-3243-y
ISSN
0163-2116
Abstract
There have been few population-based studies on the prevalences of gastroesophageal reflux disease (GERD) and dyspepsia using Rome III criteria in Asian countries. A population-based, cross-sectional study was conducted by telephone interviews of 5,000 Koreans between the ages of 20-69 years. Gastrointestinal symptoms were assessed by a translated Korean version of Rome III criteria. Uninvestigated dyspepsia (UID) was defined by symptom criteria of Rome III. GERD was defined by troublesome heartburn and/or acid regurgitation occurring at least once a week. The EQ5D assessment tool was used for the evaluation of quality of life. The prevalences of UID, postprandial distress syndrome (PDS), and epigastric pain syndrome (EPS) were 7.7, 5.6, and 4.2 %, respectively. Overlap between PDS and EPS was found in 27.1 % (104/384) of subjects with UID. There were no significant differences in demographic variables between patients with PDS and EPS. The prevalence of GERD was 7.1 %. Overlap between GERD and UID was found in 50.0 % of GERD patients. The EQ5D index of patients without either UID or GERD was 0.92 +/- A 0.07, and those of patients with only UID, with only GERD, and with both UID and GERD were 0.88 +/- A 0.09, 0.88 +/- A 0.11, and 0.84 +/- A 0.15, respectively. GERD and UID based on Rome III criteria were prevalent and significantly affected the quality of life in Korea. In Korean patients with UID, there was considerable overlap and there were no significant differences in demographic variables between PDS and EPS.
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Keum, Bora
Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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