Functional magnetic resonance cholangiography with Gd-EOB-DTPA: A study in healthy volunteers
- Authors
- Lee, Seung Wha; Cha, Sang Hoon; Chung, Hwan Hoon; Kim, Kee Hwan; Yeom, Suk Keu; Seo, Bo Kyung; Je, Bo Kyung; Kim, Baek Hyun
- Issue Date
- May-2014
- Publisher
- ELSEVIER SCIENCE INC
- Keywords
- Magnetic resonance; Bile ducts; Gastrointestinal tract; Contrast medium; Gd-EOB-DTPA
- Citation
- MAGNETIC RESONANCE IMAGING, v.32, no.4, pp 385 - 391
- Pages
- 7
- Indexed
- SCI
SCIE
SCOPUS
- Journal Title
- MAGNETIC RESONANCE IMAGING
- Volume
- 32
- Number
- 4
- Start Page
- 385
- End Page
- 391
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/9340
- DOI
- 10.1016/j.mri.2014.01.003
- ISSN
- 0730-725X
1873-5894
- Abstract
- Purpose: To describe the patterns of bile distribution in the biliary tree, duodenum, jejunum, and stomach, and to determine the gallbladder ejection fraction (GBEF) by using functional magnetic resonance cholangiography (MRC) with gadolinium-ethoxybenzyl-diethylenetriamine penta-acetic acid (Gd-EOB-DTPA) in healthy volunteers. Materials and Methods: Forty subjects were included in this study. After conventional MRC, pre-fatty meal MRC (PRFM) was obtained at 30, 40, 50, and 60 min after contrast agent injection. Then, post-fatty meal MRC (POFM) was obtained every 10 min for 1 h. We assessed the PRFM and POFM for opacification of contrast agent in the first- and second-order intrahepatic ducts (IHDs) and the common bile duct (CBD). Contrast agent opacification in the cystic duct was assessed, and the percentage volume of contrast agent filling in the gallbladder (GB) was calculated on PRFM. We calculated the GBEF and assessed the presence of contrast agent in the GB, duodenum, jejunum, and stomach. Results: Thirty-six (90%) subjects showed grade 3 CBD opacification (visible contrast and well-defined bile duct border) on 60-min PRFM. Thirty-four (85%) subjects showed grade 3 first-order IHD opacification on 60-min PRFM. All (100%) subjects showed cystic duct opacification of contrast agent, and the average percentage volume of contrast agent filling in the GB was 68.81% +/- 16.84% on 60-min PRFM. The GBEF at 30-min POFM was 35.00% +/- 18.26%. Ten (25%) subjects had no contrast agent in the stomach and small bowel on all PRFMs. Twelve (30%) subjects had contrast medium in the stomach on PRFM and/or POFM. Conclusions: Functional MRC with Gd-EOB-DTPA can allow determining the distribution of bile in the biliary tree and small intestine, as well as the GBEF. (C) 2014 Elsevier Inc. All rights reserved.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 2. Clinical Science > Department of Radiology > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.