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Survey of perinatal hepatitis B virus transmission after Korean National Prevention Program in a tertiary hospital

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dc.contributor.authorKim J.H.-
dc.contributor.authorKim J.S.-
dc.contributor.authorLee J.J.-
dc.contributor.authorKim J.H.-
dc.contributor.authorKim S.Y.-
dc.contributor.authorJung Y.K.-
dc.contributor.authorKwon O.S.-
dc.contributor.authorKim Y.S.-
dc.contributor.authorChoi D.J.-
dc.contributor.authorKim J.H.-
dc.date.available2020-11-02T19:43:18Z-
dc.date.created2020-10-19-
dc.date.issued2014-
dc.identifier.issn1226-3303-
dc.identifier.urihttps://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/9879-
dc.description.abstractBackground/Aims: The Ministry of Health and Welfare and the Korea Centers for Disease Control and Prevention in South Korea have been organizing hepatitis B virus (HBV) vertical infection prevention projects since July 2002. In this single-institute study, the results of surveys conducted in target mothers who delivered babies in a tertiary hospital were investigated and analyzed. Methods: Of the 9,281 mothers and their 9,824 neonates born between July 2002 and December 2012, 308 hepatitis B surface antigen (HBsAg)-positive mothers and their 319 neonates were selected for this study, and their records were analyzed retrospectively. Results: A total of 308 mothers were HBsAg-positive, with an HBV prevalence of 3.32% (308/9,281). There were 319 neonates born to these HBsAg-positive mothers, and 252 were confirmed to as either HBsAg-positive or -negative. Four were confirmed as HBsAg-positive, with a 1.59% (4/252) HBV vertical infection rate. All the mothers of neonates who had an HBV vertical infection were hepatitis B e antigen (HBeAg)-positive. Among the HBsAg-positive neonates, three were HBeAg-positive and had an HBV DNA titer of 1.0 × 108 copies/mL. Conclusions: The HBV prevalence of mothers was 3.32% (308/9,281), and their vertical infection rate was 1.59% (4/252). Thus, the South Korean HBV vertical infection prevention projects are effective, and, accordingly, HBV prevalence in South Korea is expected to decrease continuously. © 2014 The Korean Association of Internal Medicine.-
dc.language영어-
dc.publisherKorean Association of Internal Medicine-
dc.subjectantivirus agent-
dc.subjecthepatitis B surface antigen-
dc.subjecthepatitis B vaccine-
dc.subjecthepatitis B(e) antigen-
dc.subjectbiological marker-
dc.subjecthepatitis B surface antigen-
dc.subjecthepatitis B(e) antigen-
dc.subjectvirus DNA-
dc.subjectarticle-
dc.subjectclinical effectiveness-
dc.subjectfemale-
dc.subjecthealth program-
dc.subjecthealth survey-
dc.subjecthepatitis B-
dc.subjecthuman-
dc.subjectimmunoprophylaxis-
dc.subjectinfection prevention-
dc.subjectinfection rate-
dc.subjectmajor clinical study-
dc.subjectnewborn-
dc.subjectnewborn infection-
dc.subjectnonhuman-
dc.subjectperinatal infection-
dc.subjectpregnancy outcome-
dc.subjectprevalence-
dc.subjectretrospective study-
dc.subjecttertiary care center-
dc.subjectvertical transmission-
dc.subjectvirus transmission-
dc.subjectadult-
dc.subjectblood-
dc.subjectgenetics-
dc.subjecthepatitis B-
dc.subjectHepatitis B virus-
dc.subjectimmunology-
dc.subjectpregnancy-
dc.subjectprevention and control-
dc.subjectpublic health-
dc.subjectSouth Korea-
dc.subjecttertiary care center-
dc.subjecttransmission-
dc.subjectvirology-
dc.subjectvirus load-
dc.subjectAdult-
dc.subjectBiological Markers-
dc.subjectDNA, Viral-
dc.subjectFemale-
dc.subjectHealth Surveys-
dc.subjectHepatitis B-
dc.subjectHepatitis B e Antigens-
dc.subjectHepatitis B Surface Antigens-
dc.subjectHepatitis B virus-
dc.subjectHumans-
dc.subjectInfant, Newborn-
dc.subjectInfectious Disease Transmission, Vertical-
dc.subjectNational Health Programs-
dc.subjectPregnancy-
dc.subjectPrevalence-
dc.subjectRepublic of Korea-
dc.subjectRetrospective Studies-
dc.subjectTertiary Care Centers-
dc.subjectViral Load-
dc.titleSurvey of perinatal hepatitis B virus transmission after Korean National Prevention Program in a tertiary hospital-
dc.typeArticle-
dc.contributor.affiliatedAuthorJung Y.K.-
dc.identifier.doi10.3904/kjim.2014.29.3.307-
dc.identifier.scopusid2-s2.0-84901351665-
dc.identifier.bibliographicCitationKorean Journal of Internal Medicine, v.29, no.3, pp.307 - 314-
dc.relation.isPartOfKorean Journal of Internal Medicine-
dc.citation.titleKorean Journal of Internal Medicine-
dc.citation.volume29-
dc.citation.number3-
dc.citation.startPage307-
dc.citation.endPage314-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.isOpenAccessY-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.subject.keywordPlusantivirus agent-
dc.subject.keywordPlushepatitis B surface antigen-
dc.subject.keywordPlushepatitis B vaccine-
dc.subject.keywordPlushepatitis B(e) antigen-
dc.subject.keywordPlusbiological marker-
dc.subject.keywordPlushepatitis B surface antigen-
dc.subject.keywordPlushepatitis B(e) antigen-
dc.subject.keywordPlusvirus DNA-
dc.subject.keywordPlusarticle-
dc.subject.keywordPlusclinical effectiveness-
dc.subject.keywordPlusfemale-
dc.subject.keywordPlushealth program-
dc.subject.keywordPlushealth survey-
dc.subject.keywordPlushepatitis B-
dc.subject.keywordPlushuman-
dc.subject.keywordPlusimmunoprophylaxis-
dc.subject.keywordPlusinfection prevention-
dc.subject.keywordPlusinfection rate-
dc.subject.keywordPlusmajor clinical study-
dc.subject.keywordPlusnewborn-
dc.subject.keywordPlusnewborn infection-
dc.subject.keywordPlusnonhuman-
dc.subject.keywordPlusperinatal infection-
dc.subject.keywordPluspregnancy outcome-
dc.subject.keywordPlusprevalence-
dc.subject.keywordPlusretrospective study-
dc.subject.keywordPlustertiary care center-
dc.subject.keywordPlusvertical transmission-
dc.subject.keywordPlusvirus transmission-
dc.subject.keywordPlusadult-
dc.subject.keywordPlusblood-
dc.subject.keywordPlusgenetics-
dc.subject.keywordPlushepatitis B-
dc.subject.keywordPlusHepatitis B virus-
dc.subject.keywordPlusimmunology-
dc.subject.keywordPluspregnancy-
dc.subject.keywordPlusprevention and control-
dc.subject.keywordPluspublic health-
dc.subject.keywordPlusSouth Korea-
dc.subject.keywordPlustertiary care center-
dc.subject.keywordPlustransmission-
dc.subject.keywordPlusvirology-
dc.subject.keywordPlusvirus load-
dc.subject.keywordPlusAdult-
dc.subject.keywordPlusBiological Markers-
dc.subject.keywordPlusDNA, Viral-
dc.subject.keywordPlusFemale-
dc.subject.keywordPlusHealth Surveys-
dc.subject.keywordPlusHepatitis B-
dc.subject.keywordPlusHepatitis B e Antigens-
dc.subject.keywordPlusHepatitis B Surface Antigens-
dc.subject.keywordPlusHepatitis B virus-
dc.subject.keywordPlusHumans-
dc.subject.keywordPlusInfant, Newborn-
dc.subject.keywordPlusInfectious Disease Transmission, Vertical-
dc.subject.keywordPlusNational Health Programs-
dc.subject.keywordPlusPregnancy-
dc.subject.keywordPlusPrevalence-
dc.subject.keywordPlusRepublic of Korea-
dc.subject.keywordPlusRetrospective Studies-
dc.subject.keywordPlusTertiary Care Centers-
dc.subject.keywordPlusViral Load-
dc.subject.keywordAuthorHepatitis B-
dc.subject.keywordAuthorKorea-
dc.subject.keywordAuthorVaccination-
dc.subject.keywordAuthorVertical infection transmission-
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