Glomerular filtration rate and proteinuria: Association with mortality and renal progression in a prospective cohort of a community-based elderly population
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Oh S.W. | - |
dc.contributor.author | Kim S. | - |
dc.contributor.author | Na K.Y. | - |
dc.contributor.author | Kim K.W. | - |
dc.contributor.author | Chae D.-W. | - |
dc.contributor.author | Chin H.J. | - |
dc.date.available | 2020-11-02T19:43:57Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/9961 | - |
dc.description.abstract | Limited prospective data are available on the importance of estimated glomerular filtration rate (GFR) and proteinuria in the prediction of all-cause mortality (ACM) in community-based elderly populations. We examined the relationship between GFR or proteinuria and ACM in 949 randomly selected community-dwelling elderly subjects (aged ≥65 years) over a 5-year period. A spot urine sample was used to measure proteinuria by the dipstick test, and GFR was estimated using the chronic kidney disease-epidemiology collaboration (CKD-EPI) equation. Information about mortality and causes of death was collected by direct enquiry with the subjects and from the national mortality data. Compared to subjects without proteinuria, those with proteinuria of grade ≥1+ had a 1.725-fold (1.134-2.625) higher risk of ACM. Compared to subjects with GFR ≥90 ml/min/1.73 m2, those with GFR<45 ml/min/1.73 m2 had a 2.357 -fold (1.170-4.750) higher risk for ACM. Among the 403 subjects included in the analysis of renal progression, the annual rate of GFR change during follow-up period was -0.52±2.35 ml/min/1.73 m 2/year. The renal progression rate was 7.315-fold (1.841-29.071) higher in subjects with GFR<0 ml/min/1.73 m2 than in those with GFR ≥60 ml/min/1.73 m2. Among a community-dwelling elderly Korean population, decreased GFR of <45 ml/min/1.73 m2 and proteinuria were independent risk factors for ACM. © 2014 Oh et al. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Public Library of Science | - |
dc.title | Glomerular filtration rate and proteinuria: Association with mortality and renal progression in a prospective cohort of a community-based elderly population | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1371/journal.pone.0094120 | - |
dc.identifier.scopusid | 2-s2.0-84899433578 | - |
dc.identifier.bibliographicCitation | PLoS ONE, v.9, no.4 | - |
dc.citation.title | PLoS ONE | - |
dc.citation.volume | 9 | - |
dc.citation.number | 4 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | creatinine | - |
dc.subject.keywordPlus | aged | - |
dc.subject.keywordPlus | article | - |
dc.subject.keywordPlus | cohort analysis | - |
dc.subject.keywordPlus | creatinine urine level | - |
dc.subject.keywordPlus | dipstick test | - |
dc.subject.keywordPlus | disease association | - |
dc.subject.keywordPlus | disease course | - |
dc.subject.keywordPlus | female | - |
dc.subject.keywordPlus | follow up | - |
dc.subject.keywordPlus | glomerulus filtration rate | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | incidence | - |
dc.subject.keywordPlus | Korea | - |
dc.subject.keywordPlus | major clinical study | - |
dc.subject.keywordPlus | male | - |
dc.subject.keywordPlus | mortality | - |
dc.subject.keywordPlus | participatory research | - |
dc.subject.keywordPlus | prospective study | - |
dc.subject.keywordPlus | protein urine level | - |
dc.subject.keywordPlus | proteinuria | - |
dc.subject.keywordPlus | risk factor | - |
dc.subject.keywordPlus | urinalysis | - |
dc.subject.keywordPlus | complication | - |
dc.subject.keywordPlus | demography | - |
dc.subject.keywordPlus | disease course | - |
dc.subject.keywordPlus | kidney disease | - |
dc.subject.keywordPlus | mortality | - |
dc.subject.keywordPlus | pathophysiology | - |
dc.subject.keywordPlus | proteinuria | - |
dc.subject.keywordPlus | very elderly | - |
dc.subject.keywordPlus | Aged | - |
dc.subject.keywordPlus | Aged, 80 and over | - |
dc.subject.keywordPlus | Cohort Studies | - |
dc.subject.keywordPlus | Disease Progression | - |
dc.subject.keywordPlus | Female | - |
dc.subject.keywordPlus | Follow-Up Studies | - |
dc.subject.keywordPlus | Glomerular Filtration Rate | - |
dc.subject.keywordPlus | Humans | - |
dc.subject.keywordPlus | Kidney Diseases | - |
dc.subject.keywordPlus | Male | - |
dc.subject.keywordPlus | Prospective Studies | - |
dc.subject.keywordPlus | Proteinuria | - |
dc.subject.keywordPlus | Residence Characteristics | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
73, Goryeodae-ro, Seongbuk-gu, Seoul, Republic of Korea (02841)82-2-2286-1265
COPYRIGHT 2020 KOREA UNIVERSITY MEDICAL LIBRARY ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.