Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Analgesic efficacy of erector spinae plane block in lumbar spine surgery: A systematic review and meta-analysis

Oh, Seok KyeongLim, Byung GunWon, Young JuLee, Dong KyuKim, Seong Shin
Issue Date
Elsevier BV
Erector spinae plane block; Neurosurgical procedures; Lumbar vertebrae; Nerve block; Opioid analgesics
Journal of Clinical Anesthesia, v.78
Journal Title
Journal of Clinical Anesthesia
Study objective Erector spinae plane block (ESPB) has gained popularity for perioperative analgesia in various surgeries. However, its efficacy in lumbar surgery remains unclear. This review aimed to determine whether ESPB could improve analgesic efficacy in lumbar spine surgery. Design A meta-analysis of randomized controlled trials. Setting Perioperative setting. Patients Patients undergoing lumbar spine surgery under general anesthesia. Interventions We searched the databases including PubMed, Cochrane Library, EMBASE, Web of Science etc. for published eligible controlled trials comparing ESPB with control (no block/sham block) in lumbar spine surgery. Measurements The primary outcome was opioid consumption in the first 24 h after surgery. Main results Twelve studies comprising 665 participants were included. Compared to the control, ESPB reduced the opioid (morphine milligram equivalents) consumption significantly 24 h after surgery [mean difference (MD) = −14.55; 95% confidence interval (CI), −21.03 to −8.07; P < 0.0001] and lowered the pain scores at various time points (at rest or during movement) for 48 h after surgery. ESPB increased the patient satisfaction score (0−10) (MD = 2.38; 95% CI, 2.10 to 2.66; P < 0.0001), decreased the postoperative nausea and vomiting [risk ratio (RR) = 0.36; 95% CI, 0.20 to 0.67; P = 0.001], and minimized the length of hospital stay (MD = −1.24 days; 95% CI, −2.31 to −0.18; P = 0.02). Furthermore, subgroup analysis revealed additional reduction in opioid consumption by the block approach at the vertebral level of incision/operation than that at the fixed thoracic/lumbar level. However, considerable heterogeneity and low-grade quality of evidence were observed. Conclusions ESPB provided effective postoperative analgesia resulting in better patient satisfaction and recovery with decreased postoperative nausea and vomiting in patients undergoing lumbar surgery compared to the control. However, the low-grade quality of evidence compromised the findings, therefore further high-quality of evidence is required. PROSPERO registration number: CRD42021233362.
Files in This Item
There are no files associated with this item.
Appears in
2. Clinical Science > Department of Anesthesiology and Pain Medicine > 1. Journal Articles


Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Oh, Seok Kyeong photo

Oh, Seok Kyeong
Guro Hospital (Department of Anesthesiology and Pain Medicine, Guro Hospital)
Read more


Total Views & Downloads