The factor structure and clinical utility of clinician-rated dimensions of psychosis symptom severity in patients with recent-onset psychosis: Results of a 1-year longitudinal follow-up prospective cohort study
DC Field | Value | Language |
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dc.contributor.author | Jeong, Jae Hoon | - |
dc.contributor.author | Kim, Sung-Wan | - |
dc.contributor.author | Lee, Bong Ju | - |
dc.contributor.author | Kim, Jung Jin | - |
dc.contributor.author | Yu, Je-Chun | - |
dc.contributor.author | Won, Seung-Hee | - |
dc.contributor.author | Lee, Seung-Hwan | - |
dc.contributor.author | Kim, Seung-Hyun | - |
dc.contributor.author | Kang, Shi Hyun | - |
dc.contributor.author | Kim, Euitae | - |
dc.contributor.author | Chung, Young-Chul | - |
dc.contributor.author | Lee, Kyu Young | - |
dc.date.accessioned | 2022-08-10T00:40:37Z | - |
dc.date.available | 2022-08-10T00:40:37Z | - |
dc.date.issued | 2022-04 | - |
dc.identifier.issn | 0165-1781 | - |
dc.identifier.issn | 1872-7123 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/61302 | - |
dc.description.abstract | The classic subtype classification of schizophrenia has been removed, and DSM-5 now includes the Clinician-Rated Dimensions of Psychosis Symptom Severity (CRDPSS). In the present study, a factor analysis of the CRDPSS was performed, and we assessed whether patient classification using the derived factor structure helps predict the clinical course. The participants were 390 patients with recent-onset psychosis enrolled in the Korean Early Psychosis Cohort Study (KEPS). Two factors were identified: psychotic (including delusions, hallucinations, disorganization, and abnormal psychomotor behavior) and negative-cognitive (including negative symptoms and impaired cognition). Patients were grouped based on the factor structure and changes in clinical course were monitored over 1 year. The negative-cognitive group demonstrated longer duration of untreated psychosis, earlier onset, and a higher rate of psychiatric comorbidities. Baseline Positive and Negative Syndrome Scale (PANSS) total and Clinical Global Impression-Severity (CGI-S) scores were higher in psychotic group, but group differences were not observed after 2 months. Conversely, the PANSS negative scale score was significantly higher in negative-cognitive group throughout follow-up, and CGI-S score was reversed at 12 months. The findings indicate that the factor structure derived herein for the CRDPSS could be helpful for predicting the clinical course of recent-onset psychosis patients. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier BV | - |
dc.title | The factor structure and clinical utility of clinician-rated dimensions of psychosis symptom severity in patients with recent-onset psychosis: Results of a 1-year longitudinal follow-up prospective cohort study | - |
dc.type | Article | - |
dc.publisher.location | 아일랜드 | - |
dc.identifier.doi | 10.1016/j.psychres.2022.114420 | - |
dc.identifier.scopusid | 2-s2.0-85124327543 | - |
dc.identifier.wosid | 000829452000003 | - |
dc.identifier.bibliographicCitation | Psychiatry Research, v.310 | - |
dc.citation.title | Psychiatry Research | - |
dc.citation.volume | 310 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | ssci | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Psychiatry | - |
dc.relation.journalWebOfScienceCategory | Psychiatry | - |
dc.subject.keywordPlus | PERSISTENT NEGATIVE SYMPTOMS | - |
dc.subject.keywordPlus | UNTREATED PSYCHOSIS | - |
dc.subject.keywordPlus | 1ST-EPISODE SCHIZOPHRENIA | - |
dc.subject.keywordPlus | 1ST EPISODE | - |
dc.subject.keywordPlus | DURATION | - |
dc.subject.keywordPlus | MEDICATION | - |
dc.subject.keywordPlus | PREDICTORS | - |
dc.subject.keywordPlus | IMPACTS | - |
dc.subject.keywordPlus | DEFICIT | - |
dc.subject.keywordPlus | CLASSIFICATION | - |
dc.subject.keywordAuthor | Recent-onset psychosis | - |
dc.subject.keywordAuthor | DSM-5 | - |
dc.subject.keywordAuthor | Dimensions of psychosis | - |
dc.subject.keywordAuthor | Schizophrenia subtype | - |
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