Clinical features associated with the atrophy of fellow eyes in patients with unilateral type 3 macular neovascularization
- Authors
- Choi, Mihyun; Yoon, Eun Gyu; Nam, Ki Tae; Yun, Cheolmin
- Issue Date
- Mar-2023
- Publisher
- Kluwer Academic Publishers
- Keywords
- Type 3 macular neovascularization; Geographic atrophy; Retinal pigment epithelium and outer retinal atrophy; Age-related macular degeneration; Optical coherence tomography
- Citation
- International Ophthalmology, v.43, no.3, pp 973 - 980
- Pages
- 8
- Indexed
- SCIE
SCOPUS
- Journal Title
- International Ophthalmology
- Volume
- 43
- Number
- 3
- Start Page
- 973
- End Page
- 980
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/61466
- DOI
- 10.1007/s10792-022-02499-9
- ISSN
- 0165-5701
1573-2630
- Abstract
- Purpose
We sought to investigate the clinical features of eyes with unilateral type 3 macular neovascularization (MNV) according to the degenerative features of fellow eyes.
Methods
We retrospectively reviewed 55 patients with unilateral type 3 MNV and identified degenerative features including geographic atrophy (GA) in fellow eyes using multimodal imaging. Then, the clinical features of eyes with type 3 MNV at baseline and during follow-up with anti-vascular endothelial growth factor treatment and an as-needed regimen were compared according to the degenerative features of fellow eyes.
Results
Eighteen patients (32.7%) had GA in fellow eyes; initial disease manifestations of type 3 MNV eyes including stage, best-corrected visual acuity, and choroidal thickness (CT) did not vary between groups (all P > 0.05). During follow-up, a rate of complete fluid resolution after three monthly loading injections was not associated with GA in fellow eyes (P = 0.703), while a lower rate of early recurrence within 3 months after loading treatment was associated with thinner CT in type 3 MNV eyes and GA over one disc area in fellow eyes (P = 0.025 and P = 0.021).
Conclusion
Degenerative features of fellow eyes in patients with unilateral type 3 MNV may be associated with the clinical characteristics of affected eyes.
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Collections - 2. Clinical Science > Department of Ophthalmology > 1. Journal Articles
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