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Metabolic Syndrome in Children and Adolescents

Authors
Chung, Yoojin LindseyRhie, Young-Jun
Issue Date
Oct-2022
Publisher
EWHA Womans University School of Medicine
Keywords
Metabolic syndrome; Cardiovascular disease; Obesity; Insulin resistance; Pediatrics
Citation
EWHA Medical Journal, v.45, no.4
Indexed
ESCI
Journal Title
EWHA Medical Journal
Volume
45
Number
4
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/61867
DOI
10.12771/emj.2022.e13
ISSN
2234-3180
2234-2591
Abstract
Metabolic syndrome (MetS) is a cluster of metabolic abnormalities that include hypertension, altered glucose metabolism, dyslipidemia, and abdominal obesity and is strongly associated with an increased risk for diabetes and cardiovascular disease onset in obese adults and children. A progressively greater number of children and adolescents are being affected by this syndrome due to the constant increase in the prevalence of obesity. Like obesity, childhood MetS highly tracks to adulthood. The pathogenesis of MetS includes the interaction between obesity, insulin resistance, and inflammation. Early diagnosis and intervention are important in order to conduct lifestyle modification. In this article, we review the definition and pathophysiology of MetS, the importance of screening, and prevention and treatment options for MetS in childhood.
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Rhie, Young Jun
Ansan Hospital (Department of Pediatrics, Ansan Hospital)
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