Effect of a repeated verbal reminder of orientation on emergence agitation after general anaesthesia for minimally invasive abdominal surgery: a randomised controlled trial
- Authors
- Lee, Seohee; Sohn, Jin Young; Hwang, In Eob; Lee, Ho-Jin; Yoon, Susie; Bahk, Jae-Hyon; Kim, Bo Rim
- Issue Date
- Apr-2023
- Publisher
- Oxford University Press
- Keywords
- delirium; emergence agitation; general anaesthesia; recovery from anaesthesia; safety
- Citation
- British Journal of Anaesthesia, v.130, no.4, pp 439 - 445
- Pages
- 7
- Indexed
- SCIE
SCOPUS
- Journal Title
- British Journal of Anaesthesia
- Volume
- 130
- Number
- 4
- Start Page
- 439
- End Page
- 445
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/62878
- DOI
- 10.1016/j.bja.2022.12.009
- ISSN
- 0007-0912
1471-6771
- Abstract
- Background
An orientation strategy providing repeated verbal reminders of time, place, and person has been widely used for the non-pharmacological management of delirium. We hypothesised that using this strategy could reduce emergence agitation and improve recovery profiles.
Methods
This prospective observer-blinded RCT included male and female patients aged 18–70 yr undergoing minimally invasive abdominal surgery. During emergence from general anaesthesia, subjects in the orientation group (n=57) were provided a repeated reminder, including orientation: ‘(Patient's name), you are now recovering from general anaesthesia after surgery at Seoul National University Hospital, open your eyes!’ via noise-cancelling headphones, whereas those in the control group (n=57) only heard their name: ‘(Patient's name), open your eyes!‘. The primary outcome was the incidence of emergence agitation (Riker sedation agitation scale [SAS] ≥5). The incidence of dangerous agitation (SAS=7), maximal SAS score in the operating room, and recovery profile until 24 h postoperatively were evaluated as secondary outcomes.
Results
The incidence of emergence agitation in the operating room was significantly lower in the orientation group than in the control group (16/57 [28.1%] vs 38/57 [66.7%]; relative risk [95% confidence interval], 0.5 [0.3–0.7]; P<0.001). The incidence of dangerous agitation (0 [0.0%] vs 10 [17.5%], P=0.001) and the median maximal SAS score (4 [4–5] vs 5 [4–6], P<0.001) were also lower in the orientation group. Secondary outcomes, other than agitation-related variables, were comparable between the two groups.
Conclusions
Repeated verbal stimulation of orientation may serve as a simple and easily applicable strategy to reduce emergence agitation after general anaesthesia.
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Collections - 2. Clinical Science > Department of Anesthesiology and Pain Medicine > 1. Journal Articles
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