A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level

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초록

Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria and purpura with elevated IgA level rasing a possibility of Henoch-Scholein Purpura (H-S purpura). However, renal biopsy showed "lupus-like feature" glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. Although baseline renal function was maintained without further need for maintenance dialysis following anti-retroviral therapy (ART) and steroid, patient died from uncontrolled gastrointestinal bleeding.

키워드

Human immunodeficiency virus; glomerulonephritis; HIV-associated nephropathy; lupus nephritis; renal biopsy; IMMUNE-COMPLEX GLOMERULONEPHRITIS; CHRONIC KIDNEY-DISEASE; RENAL-DISEASE; INFECTED PATIENTS; NEPHROPATHY; PATHOLOGY; COMPONENT; EPIDEMIC; FEATURES
제목
A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level
저자
Yang, Jihyun; Seo, Min Young; Kim, Ki Tae; Lee, Jun Yong; Kim, Sun-Chul; Kim, Myung-Gyu; Jo, Sang-Kyung; Cho, Won-Yong; Kim, Hyoung-Kyu; Won, Nam Hee; Cha, Ran-Hui; Cho, Eunjung
발행일
2014
유형
Article
저널명
International Journal of Clinical and Experimental Pathology
권
7
호
7
페이지
4467 ~ 4472