Chromatic Optical Coherence Tomography for Clear and Deep-Tissue Imaging

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초록

We present a chromatic optical coherence tomography system that achieves clear and deep-tissue imaging by exploiting an intentional chromatic focal shift. A broadband light source (650-950 nm), high-NA dispersive optics, and a chromatic-gating (ChG) algorithm enable simultaneous high resolution, extended depth of focus, and strong signal-to-noise ratio. Experiments with microspheres and biological tissues demonstrate isotropic similar to 3 mu m resolution and a seven-fold depth-of-focus extension while maintaining high contrast and minimal artifacts. The proposed method provides a simple, phase-insensitive approach suitable for real-time and in vivo applications.

키워드

Optical coherence tomography; high-resolution; depth of focus (DOF); signal-to-noise ratio; deep-tissue imaging
제목
Chromatic Optical Coherence Tomography for Clear and Deep-Tissue Imaging
저자
Lee, Seung Eon; Nam, Hyeong Soo; Kim, Ryeong Hyeon; Kim, Hyun Jung; Seok, Jae Yeon; Kim, Jin Won; Kim, Young-Jin; Yoo, Hongki
DOI
10.1117/12.3098915
발행일
2026-02
유형
Proceedings Paper
저널명
Proceedings of SPIE - The International Society for Optical Engineering
권
14016