Viral shedding and environmental cleaning in middle east respiratory syndrome coronavirus infection

Citations

SCOPUS

11

초록

Viral shedding lasted 31 and 19 days from symptom onset in two patients with east respiratory syndrome coronavirus (MERS-CoV) pneumonia, respectively. Environmental real-time RT-PCR was weakly positive for bed guardrail and monitors. Even after cleaning the monitors with 70% alcohol-based disinfectant, RT-PCR was still weakly positive, and converted to negative only after wiping with diluted sodium chlorite. Further studies are required to clarify the appropriate methods to clean environments during and after treatment of patients with MERS-CoV infection. © 2015 by The Korean Society of Infectious Diseases | Korean Society for Chemotherapy.

키워드

Coronavirus; Middle East respiratory syndrome; Virus shedding; hypochlorite sodium; lopinavir plus ritonavir; peginterferon alpha2a; ribavirin; sodium chlorite; virus RNA; abdominal pain; adult; antiviral therapy; Article; case report; Coronavirus infection; coughing; diarrhea; disinfection; envelope gene; environmental sanitation; female; fever; gastrointestinal symptom; human; loading drug dose; lung disease; male; middle aged; Middle East respiratory syndrome coronavirus; Middle East respiratory syndrome coronavirus infection; multiple cycle treatment; open reading frame; pneumonia; real time polymerase chain reaction; sputum examination; thorax pain; treatment duration; viral contamination; virus gene; virus load; virus pneumonia; virus shedding; virus transmission; vomiting
제목
Viral shedding and environmental cleaning in middle east respiratory syndrome coronavirus infection
저자
Song J.Y.; Cheong H.J.; Choi M.J.; Jeon J.H.; Kang S.H.; Jeong E.J.; Yoon J.G.; Lee S.N.; Kim S.R.; Noh J.Y.; Kim W.J.
DOI
10.3947/ic.2015.47.4.252
발행일
2015
유형
Article
저널명
Infection and Chemotherapy
권
47
호
4
페이지
252 ~ 255