한국에서 1990년 발생한 급성 전염성 출혈성 질환의 혈청역학적 조사

초록

Acute hemorrhagic diseases that occurred in Korea have been confirmed as Hemorrhagic fever with renal syndrome(HFRS), Rickettsiosis and Leptospirosis among suspect hemorrhagic disease patients. In this study, we report the results of serologic test of 3,409 sera from suspect hemorrhagic disease patients in Korea, 1990. 1. Of 3,409 sera from acute hemorrhagic disease patients tested in 1990, 538 HFRS, 198 Murine typhus, 685 Scrub typhus, 50 Spotted fever and 174 Leptospirosis were confirmed serologically. 2. It was confirmed that the majority of HFRS patients occurred in Kyunggi-do, Seoul city, Chungcheongnam-do and Cheollanam-do. Murine typhus occurred mostly in Seoul, Kyunggi-do, Chungcheongnarr-do and Cheollanam-do. Scrub typhus occurred mostly in Cheollanan-do, next in Kyungsangnan-do, Seoul and Kyunggi-do, Spotted fever mostly in Seoul and Kyunggi-do, Leptospirosis in Cheollanam-do and Kyunggi-do. 3. According to the monthly incidence of acute hemorrhagic diseases, HFRS occurred mostly between October and December, Murine typhus occurred with small peak in March and April and large peak between September and December and Scrub typhus with peak between October and December same as HFRS. 4. In the sex and age distribution of acute hemorrhagic disease patients, HFRS occurred mainly in adult and the incidence of male was twice as much as that of female. Murine typhus also occurred in adult but incidence of male to female was nearly same, and Scrub typhus occurred in all age groups and there was no definite difference between the incidence of female to male. In Spotted fever incidence of male is much more than that of female, and Leptospirosis occurred chiefly in male adult patients. 5. In 1990, HFRS patient was 73 and Leptospirosis patient was 34 but only 2 Scrub typhus patients were identified in the Korean Army. Only 1 HFRS patient and 1 Spotted fever patient were confirmed in the U. S. Army. Above results revealed that in addition to HFRS patients, a large number of Murine typhus, Scrub typhus, Spotted fever and Leptospirosis patients occurred in Korea. Further seroepidemiologic study on acute hemorrhagic diseases in Jeju-do is demanded because the number of sera tested from acute hemorrhagic diseases in Jeju-do was so small.