Pulmonary fibrosis under chemotherapy with oxaliplatin, 5-fluorouracil, and leucovorin

Jung J.Y.; Hur G.Y.; Jung K.H.; Jung H.C.; Lee S.Y.; Choi I.K.; Lee S.Y.; Kim J.H.; Seo J.H.; Shin C.; Shim J.J.; In K.H.; Kang K.H.; Yoo S.H.

doi:10.4046/trd.2005.59.5.536

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Pulmonary fibrosis under chemotherapy with oxaliplatin, 5-fluorouracil, and leucovorin

Jung J.Y.;
Hur G.Y.;
Jung K.H.;
Jung H.C.;
Lee S.Y.;
... Lee S.Y.;
... Kim J.H.;
... Shin C.;
... Shim J.J.;
... Kang K.H.;
... Yoo S.H.;
외 3명

Citations

SCOPUS

1

초록

The combination of oxaliplatin, 5-fluorouracil and leucovorin (FOLFOX) has recently been shown to be beneficial in advanced colorectal and gastric cancers. The side effects of this regimen include neutropenia, diarrhea and neurosensory toxicity. However, case reports on the pulmonary toxicities of this regimen are very limited. Especially, the development of pulmonary fibrosis has never been cited in the literature. Herein is reported the case of a patient treated with oxaliplatin, 5 fluorouracil and leucovorin combination chemotherapy in whom pulmonary fibrosis developed, but which improved after steroid pulse therapy.

키워드

Chemotherapy; Fluorouracil; Leucovorin; Oxaliplatin; Pulmonary fibrosis; fluorouracil; folinic acid; oxaliplatin; steroid; adult; article; cancer combination chemotherapy; case report; colorectal cancer; drug pulse therapy; high resolution computer tomography; histopathology; human; human tissue; lung biopsy; lung emphysema; lung fibrosis; male; stomach cancer; thorax radiography

제목: Pulmonary fibrosis under chemotherapy with oxaliplatin, 5-fluorouracil, and leucovorin

저자: Jung J.Y.; Hur G.Y.; Jung K.H.; Jung H.C.; Lee S.Y.; Choi I.K.; Lee S.Y.; Kim J.H.; Seo J.H.; Shin C.; Shim J.J.; In K.H.; Kang K.H.; Yoo S.H.

DOI: 10.4046/trd.2005.59.5.536

발행일: 2005

유형: Article

저널명: Tuberculosis and Respiratory Diseases

권: 59

호: 5

페이지: 536 ~ 540

언어: KOR

출판사: 대한결핵및호흡기학회

발행국가: 대한민국

분량: 5 페이지

ISSN: E 2005-6184
P 1738-3536