Investigation of NK Cell Activity in Healthy and Immunocompromised Individuals Using Lens-Free Shadow Imaging Technology

초록

In this study, we investigate the variations in NK cell activity between healthy individuals and patients in sterile environments. We observed significant differences in NK cell activity using lens-free shadow imaging technology (LSIT). Combined shadow parameter (CSP) and innate immunity index (I-3) were derived from the shadow images obtained using LSIT. The vehicle CSP and I-3 values were significantly higher in healthy individuals than patients, indicating reduced NK cell activity in the patient group. These results emphasize the difference in immune response between healthy individuals and patients in sterile environments, highlighting the potential of LSIT for real-time immune monitoring.