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NMD Takes the Immune Road to NDD
- Kim, Eunha;
- Huh, Jun R.
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0초록
Proper mRNA quality control prevents immune activation; when it goes awry, mice and flies develop abnormal behavioral phenotypes. In this issue of Neuron, Johnson et al. (2019) report that inhibiting nonsense-mediated mRNA decay (NMD) contributes to the pathogenesis of neurodevelopmental disorder (NDD) phenotypes by triggering aberrant immune activation.
키워드
MESSENGER-RNA DECAY; PATHWAY
- 제목
- NMD Takes the Immune Road to NDD
- 저자
- Kim, Eunha; Huh, Jun R.
- 발행일
- 2019-11
- 유형
- Editorial Material
- 저널명
- Neuron
- 권
- 104
- 호
- 4
- 페이지
- 625 ~ 626
- 언어
- ENG
- 출판사
- Cell Press
- 발행국가
- 미국
- 분량
- 2 페이지
- ISSN
- E 1097-4199
P 0896-6273