실험적 뇌부종(제4) - 실험적 뇌부종에서의 뇌조직의 산소소비량 -

초록

Numerous experimental and clinical studies of brain metabolism have reported since last two decades and many authors have concentrated their effors on the metabolism of gas, glucose, electrolytes and enzymes. Oxygen and glucose that are utilized in the brain are two of the most important substances and play very important roles in the brain to form high energy bond (adenosine triphosphate) and nucleic acid. Authors have attempted to measure oxygen consumption in normal rabbit brains and diseased brains that are produced by the expansion of stalk of laminaria in the right epidural space of the rabbit. In the normal rabbits, the average value of oxygen consumption of cerebral gray and white matters were 3.44±0.29㎕ O₂/100㎎ (dry weight)/30min and 0.72±0.04 ㎕ O₂/100㎎ (dry weight)/30min respectively. The value of oxygen consumption of cerebral gray and white matters in the compressed hemisphere showed high values than those in control group, and they revealed a tendency of rather rapid increase at an early experimental stage, and of gradual decrease thereafter.