Innovative approach of nanopore-based metagenomic sequencing for rapid identification of bacterial pathogens in joint fluid: A pilot study

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초록

Analysis of 11 clinical samples of joint fluid in this pilot study demonstrated proof-of-concept for nanopore-based metagenomic sequencing to serve as a complementary real-time diagnostic technique for septic arthritis, with a sensitivity of 75.0 % and specificity of 57.1 %, compared to the gold standard method of bacterial culture. © 2024

키워드

Infectious arthritis; Nanopore sequencing; Point-of-care testing; Synovial fluid
제목
Innovative approach of nanopore-based metagenomic sequencing for rapid identification of bacterial pathogens in joint fluid: A pilot study
저자
Sung, Yoon Hyun; Jeong, Woong Kyo; Lee, Hak Jun; Suh, Jin Woong; Kim, Jeong Yeon; Yoon, Young Kyung
DOI
10.1016/j.diagmicrobio.2024.116545
발행일
2024-12
유형
Article
저널명
Diagnostic Microbiology and Infectious Disease
권
110
호
4