筋弛緩劑가 眼壓에 미치는 影響

초록

The purpose of this experiments were to evaluate the effect of muscle relaxants on the intraocular pressure during general anesthesia for intraocular surgery. Forty patients in American Society of Anesthesiologists Physical status Ⅰ and Ⅱ aged from 19 to 60 years were studied during anesthesia for elective surgery and gave history of eye disease. All were premedicated with 50㎎ of meperidine and 0.5㎎ of atropine. Before induction intraocular pressure was measured and defined control value. Anesthesia were induced with 2.5% thiopental sodium and succinylcholine chloride and intraocular pressure was measured after endotracheal intubation. Anesthesia were maintained by morphine, haloperidol, nitrous oxide, and oxygen. Tubocurarine and pancuronium were administered on the return of spontaneous respiration. following succinylcholine chloride. Subsequent measurement were 5, 10, 20 minutes after tubocurarine and pancuronium administration respectively. The results were as follows; 1. Succinylcholine chloride caused a significant rise in intraocular pressure. 2. Pancuronium caused a significant decrease in intraocular pressure. 3. Tubocurarine caused a significant decrease in intraocular pressure.

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