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Ceria nanoparticles that can protect against ischemic stroke
- Kim C.K.;
- Kim T.;
- Choi I.-Y.;
- Soh M.;
- Kim D.;
- 외 11명
Citations
SCOPUS
559초록
Uniform 3 nm-sized ceria nanoparticles can protect against ischemic stroke by scavenging reactive oxygen species (ROS) and reducing apoptosis. PEGylated ceria nanoparticles showed protective effects against ROS-induced cell death in vitro. Optimal doses of ceria nanoparticles reduced infarct volumes and the rate of ischemic cell death in vivo. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
키워드
apoptosis; ceria nanoparticles; ischemic stroke; reactive oxygen species; therapeutic agents; Ceria nanoparticles; In-vitro; In-vivo; Ischemic strokes; Protective effects; Reactive oxygen species; Therapeutic agents; Cerium compounds; Nanoparticles; Oxygen; Cell death; cerium; metal nanoparticle; reactive oxygen metabolite; scavenger; animal; article; brain ischemia; cell death; cell survival; cerebrovascular accident; chemistry; CHO cell; disease model; dose response; drug effect; hamster; metabolism; rat; tissue distribution; Animals; Brain Ischemia; Cell Death; Cell Survival; Cerium; CHO Cells; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Metal Nanoparticles; Rats; Reactive Oxygen Species; Stroke; Tissue Distribution
- 제목
- Ceria nanoparticles that can protect against ischemic stroke
- 저자
- Kim C.K.; Kim T.; Choi I.-Y.; Soh M.; Kim D.; Kim Y.-J.; Jang H.; Yang H.-S.; Kim J.Y.; Park H.-K.; Park S.P.; Park S.; Yu T.; Yoon B.-W.; Lee S.-H.; Hyeon T.
- 발행일
- 2012
- 유형
- Article
- 권
- 51
- 호
- 44
- 페이지
- 11039 ~ 11043
- 언어
- ENG
- 출판사
- John Wiley & Sons Ltd.
- 발행국가
- 독일
- 분량
- 5 페이지
- ISSN
- E 1521-3773
P 1433-7851