Corticosteroid Treatment of Pure Red Cell Aplasia in a Patient with Hepatitis A

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초록

Secondary pure red cell aplasia (PRCA), as an extrahepatic manifestation of hepatitis A virus infection, has been reported on rare occasions. We report herein an unusual case of hepatitis A complicated by PRCA. In addition, we reviewed nine cases reported in the English literature. Our case of non-fulminant hepatitis A complicated by PRCA and hemolytic anemia was successfully treated with initial transfusion and corticosteroid therapy for 18 weeks. The patient's hematologic abnormalities and liver function tests re-normalized completely. We review clinical features and effective therapeutic strategies for this disease entity. Copyright (C) 2012 S. Karger AG, Basel

키워드

Anemia; Corticosteroid; Hemolytic anemia; Hepatitis A; Pure red cell aplasia; VIRAL-HEPATITIS; HEMOLYTIC-ANEMIA; INFECTION; VIRUS
제목
Corticosteroid Treatment of Pure Red Cell Aplasia in a Patient with Hepatitis A
저자
Yoon, Young Kyung; Park, Dae Won; Sohn, Jang Wook; Kim, Min Ja; Kim, Insun; Myung Hyun Nam
DOI
10.1159/000337342
발행일
2012
유형
Article
저널명
Acta Haematologica
권
128
호
1
페이지
60 ~ 63