Adult-onset lichen striatus versus adult blaschkitis: a clinicopathological review of 40 cases of acquired blaschkolinear inflammatory dermatosis

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초록

Background Since the first description of adult blaschkitis (AB), the existence of this entity has been a matter of great debate. Objectives To compare clinicopathological features of lichen striatus (LS) and AB cases. Materials and Methods: We retrospectively reviewed the clinicopathological features of patients who clinically showed linear inflammatory dermatosis along Blaschko's lines based on a skin biopsy registry. Results Through a process of clinicopathological differential diagnosis, 27 cases of LS, three of AB, eight of linear lichen planus, and two of linear psoriasis were identified. Clinicopathological differences between LS and ABwere mostly insignificant except for age at onset and multiple site involvement. In these cases, females were affected more frequently than males. The mean age at onset was 31.6 years, and the most common involved site was the leg. The lesions lasted approximately 8.3 months with few relapses. The most common histopathological finding was perivascular infiltration followed by peri-appendageal infiltration. Conclusion Distinction between LS and AB appears to be unnecessary given their overlapping features.

키워드

acquired blaschkolinear inflammatory dermatoses; adult blaschkitis; lichen striatus; linear lichen planus; linear psoriasis; PIMECROLIMUS; LINES
제목
Adult-onset lichen striatus versus adult blaschkitis: a clinicopathological review of 40 cases of acquired blaschkolinear inflammatory dermatosis
저자
Baek, Yoo Sang; Seo, Ji Yun; Seo, Soo Hong; Ahn, Hyo Hyun; Song, Hae Jun; Kye, Young Chul; Kim, Aeree; Jeon, Jiehyun
DOI
10.1684/ejd.2019.3556
발행일
2019-05
유형
Review
저널명
European Journal of Dermatology
권
29
호
3
페이지
281 ~ 286