The effect of oral cola ingestion for the endoscopic inspection of remnant stomach - randomised case control study

초록

Backgrounds The aim of this study is to evaluate the efficacy of cola in the evening as the preparation for upper gastrointestinal endoscopy in patients who have taken distal gastrectomy. Methods A total of 70 patients who had taken subtotal gastrectomy were randomly assigned to 2 groups (group A: 33 for preparation with cola, group B: 37 for control), from July to August, 2007. The degree of residual food (grade 0: no food, grade 1: small amount of residual food, grade 2: a moderate amount, but possible to observe entire surface with body rolling, grade 3: a moderate amount, which hinders observation of the entire surface even with body rolling, grade 4: a great amount, for which endoscopic observation is impossible) and bile reflux (grade 0: absence of bile reflux, grade 1: presence of bile reflux but possible to observe entire surface without saline irrigation, grade 2: presence of bile reflux and impossible to observe entire surface without saline irrigation) were assigned by Japanese classification. Results Grade of residual food was not different, but that of bile reflux was significantly lower in group A (P=0.015). Furthermore, cola preparation significantly lowered residual food (adjusted OR: 0.032, 95% CI:0.001–0.42, P=0.001) and bile reflux (adjusted OR: 0.102, 95% CI:0.03–0.43, P=0.001) by multiple logistic regression analysis. Conclusions Preparation with cola in the evening before procedure maybe helpful for effective upper GI endoscopy and provide a good quality of bowel preparation in patient with remnant stomach.