Effectiveness of A Fourth Dose of COVID-19 mRNA Vaccine in the Elderly Population During the Omicron BA.2 and BA.5 Circulation: A Nationwide Cohort Study in Korea (K-COVE)

초록

Effectiveness of 4th dose booster of COVID-19 mRNA vaccine in Korean adults aged >=60 years during Omicron BA.2 and BA.5 circulation against critical infection was 67.7% (95% CI 50.7%-78.8%) at 31-60 days and 62.1% (45.5%-73.7%) at 61-90 days. We estimate the effectiveness of a fourth dose booster of coronavirus disease 2019 mRNA vaccine in individuals aged & GE;60 years during Omicron BA.2 and BA.5 circulation in Korea. The effectiveness against critical infection was 67.7% (95% confidence interval, 50.7%-78.8%) at 31-60 days and 62.1% (95% confidence interval, 45.5%-73.7%) at 61-90 days.

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