홍역의 효율적 예방: 홍역감염의 분자유전학적 및 역학적 연구

초록

IV. Results From July 1994 to November 1997, The measles specific antibodies of pregnant women and their newbom babies(44 couples), nonvaccinated infants(91), vaccinated infants and pnmar school children in Seoul(275), middle and high school students(216), and adults over 20year-old were tested, and measled children(80) were invested for genetic studies and virus isolations. Vaccination or disease record was investigated by medical records, vaccination record, direct question to their parents and/or questionaire. We measured antibody titers of parturient women and umbilical cord sera of their newboms, passive antibody titers after vaccination in nonvaccinated infants, in different number of vaccination and changes of antibody titers with age after vaccination. In addition, we tried isolation of virus from specimen of measled patients and did the cloning and expression of measles specific H gene.