서울 서남부지역 노인인구에서 공복혈당 및 경구 당부하검사 (ADA 및 WHO 당뇨병 진단기준)에 의한 당뇨병의 유병률 (SWS(SouthWest Seoul) Study)

초록

BACKGROUND: The prevalence of diabetes in Korea is increasing rapidly, however we do not have much reliable data to prove it. Thus, the Southwest Seoul Study (SWS Study) designed to investigate the prevalence of diabetes (Clinical impact of new diagnostic criteria of ADA compare to the one of WHO), other metabolic diseases, and the proportion of diabetes related mortalities in the elderly Korean southwest Seoul population in prospectively. However, in this report we summarized the prevalence of diabetes only. METHODS: Randomly selected 1,737 elderly subjects over 60 years who lived in southwest area of Seoul were recruited in this study. Subjects underwent 75 g OGTT, interviewed using the standardized questionnaire, and careful physical examinations during the evaluation. Biochemical data were collected from 1,652 subjects and were analysed for this report. Of 1,652 subjects, we identified 196 pre-diabetics. However, these subjects were included in this analysis. ADA criteria (FBS> 126 mg/dL (7.0 mmol/L)) and WHO criteria (75 gOGTT, pp2h ≥ 200 mg/dL (11.1 mmol/L)) were used as the criteria for diagnosis of diabetes. ADA and WHO criteria for impaired glucose tolerance (IGT, WHO: FBS<7.0 mmol/L, 7.8 mmol/L≤ pp2h < 11.1 mol/L), and impaired fasting glucose (IFG, ADA:6.1 mmol/L ≤ FBS <7.0 mmol/L, pp2h <7.8 mmol/L) were also used. Results: The prevalence of Diabetes mellitus was 20.5% (previous diagnosed 196 people (11.9%), newly diagnosed 142 people (8.6%); total 338 people). Among 142 newly diagnosed people, 50 people diagnosed by new ADA criteria and 129 people were diagnosed by WHO criteria, thirty seven people were diagnosed by the both criteria. The number of IGT and IFG were 337 (20.4%) and 85 (5.1%)people, respectively. CONCLUSION: The prevalence of diabetes in Korean elderly who lived in southwest area of Seoul was 20.4%. The prevalence of IGT and IFG were 20.4%, 5.1%, respectively. Furthermore, this study suggest that using the ADA fasting criteria only for screening of diabetes might cause under diagnose of diabetes in elderly Korean.

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