기쿠치씨 병의 임상적 고찰

초록

Background and Objectives: Kikuchi’s disease, also known as various terms, is the benign self limiting dis-ease of unknown origin. It causes cervical lymphadenitis, usually in young women with frequent fever. Also it may be mistaken for malignant lymphoma or other systemic granulomatous inflammatory disease. The purpose of this study is to report the characteristics of clinical, laboratory and pathologic findings of Kikuchi’s disease. Materials and Methods: We evaluated 29 patients, who were diagnosed as Kikuchi’s disease with excisional biopsies, retrospectively. Results: There was female predilection and the most common presenting symptoms was fever. The common involvement site were superior and inferior internal jugular chain and spinal accessory chain. Laboratory findings revealed that leukopenia and high ESR (erythrocyte sedimentation rate) were noted and admixture of monocyte and histiocyte with karyorrhetic debris were observed in the biopsy specimen. Only two of twelve cases were positive finding of Kikuchi’s disease on fine-needle aspiration cytology. Conclusions: We described 29 cases of Kikuchi’s disease with clinical, laboratory and pathologic findings and reviewed the literature. And it will be needed further study to improve the technique and accuracy of fine- needle aspiration cytology.

키워드