Venous valve like mono-leaflet micro valve and its integration with pumping system

초록

Delivery of small volumetric-sensitive materials using a micro pumping system has become a pressing issue in the fields of chemistry, biology, and medicine. In this paper, we present a simple check valve whose operation mimics that of venous valves which is constructed via the in-situ fabrication method[1]. We constructed the micro pumping system by combining two venous-like check valves with an oscillating polymeric diaphragm driven by pneumatic force. We evaluated the performance of the pumping system, and also we investigated the feasibility of a novel PDMS-based micro total cell culturing system(uμTCCS) having addressable cell-delivering and cell culturing functions on a single platform. © 2006 Society for Chemistry and Micro-Nano Systems.