호르몬 대체요법을 받고있는 폐경후 여성에서 부정기 질 출혈과 동반된 부인과적 처치: 주기적 호르몬 대체요법과 지속적 병합 호르몬 대체요법의 비교

초록

Objective: To measure gynecologic resources required to care for women who have unscheduled vaginal bleeding while using hormone replacement therapy. Materials and Methods: Between January 1996 to December 1998, women presenting with abnormal withdrawal bleeding on HRT were identified and associated clinic visits and gynecologic procedures were recorded during a mean follow-up of 2 years. Results: Among women using cyclic HRT, 28.9% had≥1 visit for unscheduled vaginal bleeding 8.7% had≥1 endometrial biopsy. Among women using continuous combined HRT, 19.3% had≥1 visit for unscheduled vaginal bleeding and 6.4% had≥1 endometrial biopsy. The gynecologic procedures used in women using cyclic HRT were 20% of reassurance, 50% of ultrasonograpy, 30% of endometrial biopsy and in women using continuous combined HRT were 50% of reassurance, 16.6% of ultrasonograpy, 33.3% of endometrial biopsy. The results of endometrial biopsy were reported all the benign condition. Conclusion(s): Unscheduled vaginal bleeding markedly decreased after 12 months of therapy in women using continuous combined HRT but did not decline among those using cyclic HRT.

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