건강 성인에서 Dual Probe를 이용한 24시간 보행성 식도pH 검사

초록

Background/Aims: Ambulatory 24-hr esophageal pH monitoring is considered the gold standard for diagnosing gastroesophageal reflux disease (GERD). The aims of this study were to define normal value of proximal and distal esophageal pH monitoring in healthy Koreans and to determine pH criteria that optimally defines acid reflux in the proximal esophagus. Methods: Twenty-five healthy subjects underwent 24 hr ambulatory esophageal dual probe pH monitoring. The pH values of the proximal and distal esophagus were measured and ΔpH in the proximal esophagus was calculated. ΔpH was then used to determine the likelihood of a true reflux event. Results: In the proximal esophagus, the mean total fraction time at pH <4 was 0.27% and the 95th percentile was 0.95%. In the distal esophagus, the mean total fraction time at pH <4 was 1.42% and the 95th percentile was 3.63%. Proximal esophageal acid reflux was significantly associated with distal esophageal acid reflux when the proximal esophageal reflux occurred at pH <4 and ΔpH ≥2. Conclusions: In healthy Koreans, the reflux parameters were similar to those of Western populations. Optimal criteria for proximal esophageal acid reflux was ΔpH ≥2 and pH <4. (Korean J Gastroenterol 2001;37:1-6)

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