Comparison of sporadic sclerotic fibroma and solitary fibrous tumor in the oral cavity

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초록

Sporadic sclerotic fibroma (SF) and solitary fibrous tumor (SFT) arising in the oral cavity are very rare. In this report, we describe two cases of oral pathology, one involving SF and the other involving SIFT. Both cases presented with well-circumscribed, firm nodules with similar gross findings. However, the histologic findings of the SF and SFr showed rather distinct features. The SF was composed of hyalinized sclerotic collagen bundles arranged in a whorled pattern, whereas the SFT was formed by spindles cells arranged in hypo- and hypercellular areas. The immunohistochemical findings were similar in both cases; there was positivity for vimentin, CD34, and CD99, but bcl-2 positivity was only seen in the SFT. Although their histopathologies are similar, SF and SFT should be considered in the differential diagnosis of soft tissue tumors in the oral cavity.

키워드

sclerotic fibroma; solitary fibrous tumor; oral cavity; bcl-2; COWDENS-DISEASE; MULTIPLE HAMARTOMA; SOFT-TISSUES; TONGUE; EXPRESSION; MUCOSA; SKIN
제목
Comparison of sporadic sclerotic fibroma and solitary fibrous tumor in the oral cavity
저자
Lee, Ju-Han; An, Jung-Suk; Lee, Eung Seok; Kwon, Soon-Young; Kim, Young-Sik
DOI
10.3349/ymj.2007.48.3.535
발행일
2007-06-30
유형
Article
저널명
Yonsei Medical Journal
권
48
호
3
페이지
535 ~ 539