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초록
Epidermal growth factor (EGF) has an important role in the regulation of the proliferation and differentiation of epidermal keratinocytes, as well as in the survival, angiogenesis and metastasis of various cancer cells. There have been some reports of acneiform skin lesions that occurred in the cancer patients treated with ZD1839(Iressa®), an inhibitor of EGF tyrosine kinase. We report a case of acneiform eruption related to the anticancer drug, ZD1839(Iressa®).
키워드
Acneiform eruption; ZD1839; epidermal growth factor; gefitinib; acne; acneiform skin eruption; adult; angiogenesis; article; cancer cell; case report; cell differentiation; cell proliferation; cell survival; epidermis cell; female; human; human tissue; keratinocyte; metastasis; rash
- 제목
- ZD1839(Iressa(R)) 복용 후 발생한 여드름모양 발진 1예
- 제목 (타언어)
- A case of acneiform skin eruption associated with ZD1839(Iressa®)
- 저자
- 김용주; 황규철; 유동수; 오칠환; 송해준
- 발행일
- 2004-04
- 유형
- Article
- 저널명
- 대한피부과학회지
- 권
- 42
- 호
- 4
- 페이지
- 478 ~ 481
- 언어
- KOR
- 출판사
- 대한피부과학회
- 발행국가
- 대한민국
- 분량
- 4 페이지
- ISSN
- P 0494-4739