삼일열 말라리아의 감염시 혈중 지질변화

초록

Background : Alteration in plasma lipid levels during malaria attacks was studied to evaluate the diagnstic values in vivax malaria. Methods : The plasma levels of total cholesterol, triglycerides, HDL-cholesterol (HDL-c), and LDL-cholesterol (LDL-c) were analyzed and compared in 32 patients with vivax malaria at presentation, in 10 patients after 17-days of treatment with anti-malaria drug, and in 40 control individuals. Interrelation of lipid profile with other parameters including parasitemia level, platelet count, hemoglobin and WBC counts were analysed. Results : In patients with malaria, serum total cholesterol, triglycerides, HDL-c and LDL-c concentrations were significantly lower than those of control subjects. None of lipid profile showed any correlation with the parasitemia level. After treatment, HDL-c was significantly elevated. Conclusion : These results suggest that lipid profile, especially decreased of HDL-c, may be a valuable information in the diagnosis of the malaria. (Korean J Infect Dis 33:58∼61, 2001)

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