흰쥐 자궁의 감각신경의 분포상태와 전도경로에 관한 연구

초록

Although efferent neural control of the uterus has been studied extensively, little is known for its afferent sensory supply. To make certain whether the uterus of the rat, like that of the rabbit and cat, is supplied with afferent sensory fibers or not, and, if so, to confirm the segments through which these afferents enter the spinal cord, we used the tract-tracing technique using HRP or WGA-HRP in the virgin Sprague-Dawley rats. The results are as followings. 1. WGA-HRP injection labelled 30 times more dorsal root ganglion cells than HRP injection did. 2. Afferent fibers originated mostly at the cervix and body(98.5%) and only a small portion(1.5%) originated at the horns. 3. Labelled dorsal root ganglion cells from the uterine cervix or body were found in 712-L4 ganglia(73%) and in LS-51 ganglia(27%) with the largest number occuring in Ll. This result shows that the afferent sensory fibers from the cervix and body of virgin rat enter the spinal cord predominantly through the hypogastric nerve, but also through the pelvic nerve. 4. Labelled dorsal root ganglion cells from the horns were found only in 713-L3 ganglia with the largest number occurring in L2. This result shows that the afferent sensory fibers from the horns enter the spinal cord through the hypogastric nerve only. 5. The average diameter of labelled ganglion cells was 27㎛(15-46 ㎛), and the distribution pattern was unipolar having 23㎛ as a peak.