Comparison of axial length measurement in eyes with chorioretinal diseases using spectral-domain optical coherence tomography-based device and partial coherence interferometry

초록

Purpose : Only a few studies have evaluated the reliability and comparability of axial length measurement using various ocular biometry devices in eyes with chorioretinal diseases. Partial coherence interferometry has been most widely used to measure the axial length of the eye, but devices using various principles have recently been developed. We compared the axial length measurement between partial coherence interferometry and spectral-domain optical coherence tomography (SD-OCT)-based devices. Methods : This instrument validation and comparative study, which was conducted prospectively and retrospectively, included patients with various chorioretinal diseases and healthy subjects. All patients underwent axial length measurement using a recently introduced SD-OCT-based device (HOCT-1F; Huvitz Co., Ltd., Anyang-si, South Korea) and a partial coherence interferometry (IOLMaster, version 5.4, Carl Zeiss Meditec). We compared the axial lengths measured by two devices and evaluated their agreement using the intraclass coefficient (ICC) and the Bland-Altman plots with 95% limits of agreement (LOA). Results : A total of 151 eyes of 87 patients were included, and the mean age was 63.3 ± 10.0 years. Of 151 eyes, 22 were healthy controls and 129 had chorioretinal diseases. The mean axial length measured by OCT-based device and partial coherence interferometry was 23.72 ± 0.88 mm and 23.63 ± 0.91 mm, respectively. The mean difference in axial length between the two devices was significant both in healthy controls (P = 0.0048) and in eyes with chorioretinal diseases (P < 0.001). However, the axial length measured by two devices showed excellent agreement both in healthy controls (ICC = 0.992) and in eyes with chorioretinal disease (ICC = 0.991). In Bland-Altman analysis, the mean difference of axial length in healthy controls and in eyes with chorioretinal disease was 0.099 ± 0.144 (95% LOA, -0.183–0.381) and 0.088 ± 0.168 mm (95% LOA, -0.241–0.146), respectively. Conclusions : The new SD-OCT-based device showed a good agreement with partial coherence interferometry. Axial length measured by SD-OCT-based devices are compatible, but some correction factor is required.