알레르기 비염 치료의 최신지견

Current trends in treatment of allergic rhinitis
Citations

SCOPUS

3

초록

Allergic rhinitis is an IgE-mediated disease, leading to inflammation of the nasal mucosa. Typical symptoms of allergic rhinitis are nasal congestion, rhinorrhea, sneezing, and/or nasal itching. Allergic rhinitis is a major health problem worldwide that causes illness and disability in daily life, affecting social life, sleep, school, and work. The economic cost of allergic rhinitis is substantial. Management of allergic rhinitis can be categorized largely into?allergen avoidance,?pharmacotherapy,?immunotherapy, and?surgical treatment. Although the general consensus is that allergen avoidance should lead to an improvement of symptoms, it is nearly impossible to completely avoid all allergens in real life. The importance of allergen avoidance is that minimizing allergen exposure can decrease medication dosage. Pharmacotherapy of allergic rhinitis may include any of histamine antagonist, topical/oral corticosteroid, leukotriene antagonist, decongestant, mast cell stabilizer, and cholinergic antagonist alone or in combination. Oral and intranasal spray of these medications are the main routes of administration. Immunotherapy is the medical procedure that uses controlled exposure to known allergens to reduce the severity of allergic disease. There are two ways of administering this treatment: subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT). Surgical treatment of the allergic rhinitis patient aims to resolve nasal obstruction by performing septoplasty or turbinoplasty.

키워드

Allergen avoidance; Allergic rhinitis; Immunotherapy; Pharmacotherapy; Surgical treatment; alimemazine; antihistaminic agent; brompheniramine; carbinoxamine; chlorpheniramine; cholinergic receptor blocking agent; clemastine; corticosteroid; cyclizine; cyproheptadine; decongestive agent; diphenhydramine; doxylamine; histamine release inhibitor; hydroxyzine; leukotriene receptor blocking agent; meclozine; mepyramine; promethazine; tripelennamine; triprolidine; allergic rhinitis; Article; cost of illness; human; immunotherapy; nasal pruritus; nose obstruction; nose reconstruction; nose septum reconstruction; rhinorrhea; school; sleep; sneezing; social life; subcutaneous immunotherapy; sublingual immunotherapy; trend study; turbinoplasty; work
제목
알레르기 비염 치료의 최신지견
제목 (타언어)
Current trends in treatment of allergic rhinitis
저자
Kim, Ha Kyun; Kim, Tae Hoon
DOI
10.5124/jkma.2016.59.4.300
발행일
2016-04
유형
Article
저널명
Journal of the Korean Medical Association
권
59
호
4
페이지
300 ~ 308