폐의 신경내분비암 질환군: 방사선학적 및 병리학적 소견

초록

Pulmonary neuroendocrine carcinoma constitutes a spectrum of malignancies and histopathologically, is classified into four distinct subtypes. At one end of this spectrum are typical carcinoids, low grade carcinomas with a low incidence of metastasis and excellent prognosis following surgical resection. At the other end is small cell carcinoma which typically metastasize early in their course, and for which surgery is rarely curative. Atypical carcinoids have an intermediate grade of malignancy, and their prognosis is somewhere between that of typical carcinoids and small cell carcinoma. Large cell neuroendocrine carcinoma is a high grade tumor that morphologically and biologically is between atypical carcinoids and small cell carcinoma. A knowledge of the radiologic findings of these tumors allows an appropriate differential diagnosis and can help avoid diagnostic pitfalls.

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