Association between Microbiota and Nasal Mucosal Diseases in terms of Immunity

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초록

The pathogenesis of nasal inflammatory diseases is related to various factors such as anatomical structure, heredity, and environment. The nasal microbiota play a key role in coordinating immune system functions. Dysfunction of the microbiota has a significant impact on the occurrence and development of nasal inflammation. This review will introduce the positive and negative roles of microbiota involved in immunity surrounding nasal mucosal diseases such as chronic sinusitis and allergic rhinitis. In addition, we will also introduce recent developments in DNA sequencing, metabolomics, and proteomics combined with computation-based bioinformatics.

키워드

microbiota; nasal mucosa; immunity; chronic rhinosinusitis; allergic rhinitis; CHRONIC RHINOSINUSITIS PHENOTYPES; THYMIC STROMAL LYMPHOPOIETIN; UPPER RESPIRATORY-TRACT; GUT MICROBIOTA; STAPHYLOCOCCUS-AUREUS; ALLERGIC RHINITIS; CLINICAL SEVERITY; BACTERIA; HEALTHY; DIVERSITY
제목
Association between Microbiota and Nasal Mucosal Diseases in terms of Immunity
저자
Tai, Junhu; Han, Mun Soo; Kwak, Jiwon; Kim, Tae Hoon
DOI
10.3390/ijms22094744
발행일
2021-05
유형
Review
저널명
International Journal of Molecular Sciences
권
22
호
9