Oradexon의 건초막내 주입이 건유착에 미치는 영향에 관한 실험적 연구

초록

Surgical repair of tendon lacerations in the hand is frequently unsatisfactory because of the formation of peritendinous adhesions which impede smooth glidng motion of the tendon. Numerous materials and drugs have been used to limit the formation of peritendinous adhesions without interfering of tendon healing and sliding. Author's experimental study is focused on the effects of infiltration of the oradexon into the tendon sheath upon the peritendinous adhesion in the adult rabbits. Twenty rabbits were divided, into two groups, each group comprised 10 rabbits. In group 1, oradexon was infiltrated into the tendon sheath after Bunnell suture of divided flexor digitorum longus, and in group 2, oradexon was not infiltrated into the tendon sheath after Bunnell suture. The results obtained are as follows: 1. Inflammatory reactions at the suture line were no great difference between the two experimental groups during the first week and were disappeared in the oradexon treated group more faster than in the nontreated group from the second week. 2. In the oradexon treated group, arrangement of fibroblast was much more irregular than in the nontreated group. 3. In the oradexon treated group, peritendinous covering was much more thinner than in the nontreated group.

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