A nationwide seroepidemiology of hepatitis C virus infection in South Korea
DC Field | Value | Language |
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dc.contributor.author | Kim, Do Young | - |
dc.contributor.author | Kim, In Hee | - |
dc.contributor.author | Jeong, Sook-Hyang | - |
dc.contributor.author | Cho, Yong Kyun | - |
dc.contributor.author | Lee, Joon Hyoek | - |
dc.contributor.author | Jin, Young-Joo | - |
dc.contributor.author | Lee, Don | - |
dc.contributor.author | Suh, Dong Jin | - |
dc.contributor.author | Han, Kwang-Hyub | - |
dc.contributor.author | Park, Neung Hwa | - |
dc.contributor.author | Kang, Ha Yan | - |
dc.contributor.author | Jung, Young Kul | - |
dc.contributor.author | Kim, Young Seok | - |
dc.contributor.author | Kim, Kyung-Ah | - |
dc.contributor.author | Lee, Youn Jae | - |
dc.contributor.author | Lee, Byung Seok | - |
dc.contributor.author | Yim, Hyung Joon | - |
dc.contributor.author | Lee, Heon Ju | - |
dc.contributor.author | Baik, Soon Koo | - |
dc.contributor.author | Tak, Won Young | - |
dc.contributor.author | Lee, Sun Jae | - |
dc.contributor.author | Chung, Woo Jin | - |
dc.contributor.author | Choi, Sung-Kyu | - |
dc.contributor.author | Cho, Eun-Young | - |
dc.contributor.author | Heo, Jeong | - |
dc.contributor.author | Kim, Dong Joon | - |
dc.contributor.author | Song, Byung-Cheol | - |
dc.contributor.author | Kim, Man Woo | - |
dc.contributor.author | Lee, Jun | - |
dc.contributor.author | Chae, Hee Bok | - |
dc.contributor.author | Choi, Dae Hee | - |
dc.contributor.author | Choi, Hwa Young | - |
dc.contributor.author | Ki, Moran | - |
dc.date.available | 2020-11-02T21:43:42Z | - |
dc.date.issued | 2013-04 | - |
dc.identifier.issn | 1478-3223 | - |
dc.identifier.issn | 1478-3231 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/10843 | - |
dc.description.abstract | Background & Aims The aim of this study was to reveal nationwide seroprevalence of HCV infection in South Korea by a large-scale survey. Methods From January to December 2009, a total of 291314 adults underwent health check-up in 29 centres nationwide. The data concerning anti-HCV antibody and biochemical tests were obtained from all participants. Among subjects with positive anti-HCV, such data as HCV RNA, genotypes and treatment detail were additionally analysed. Results Using an estimated 2009 population of Korea, the age, sex and area-adjusted anti-HCV positive rate was 0.78%. Anti-HCV prevalence in female patients (0.83%) was higher than that in male patients (0.75%). Gradual increase in anti-HCV positivity was observed, from 0.34% in those aged 2029years to 2.31% in those >70years. The age- and sex-adjusted anti-HCV prevalence varied in different areas, being higher in Busan and Jeonnam (1.532.07%), mid-level in Seoul and surrounding districts (0.500.61%) and lower in Jeju (0.23%). The comparative analysis of laboratory variables between anti-HCV (+) and anti-HCV () group revealed significantly higher levels of alanine aminotransferase and lower levels of serum lipids in anti-HCV (+) group. Among 1 718 anti-HCV positive subjects, serum HCV RNA was measured only in 478 people, of whom 268 (56.1%) patients had detectable HCV RNA in serum. Among 50 patients for whom assessment of response to antiviral therapy was feasible, overall sustained virological response was achieved in 84% of patients. Conclusion The prevalence of HCV infection is low in South Korea. Studies to analyse risk factors are warranted to reduce HCV infection. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | WILEY | - |
dc.title | A nationwide seroepidemiology of hepatitis C virus infection in South Korea | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1111/liv.12108 | - |
dc.identifier.scopusid | 2-s2.0-84875054629 | - |
dc.identifier.wosid | 000316228600012 | - |
dc.identifier.bibliographicCitation | LIVER INTERNATIONAL, v.33, no.4, pp 586 - 594 | - |
dc.citation.title | LIVER INTERNATIONAL | - |
dc.citation.volume | 33 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 586 | - |
dc.citation.endPage | 594 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | UNITED-STATES | - |
dc.subject.keywordPlus | GENOTYPE DISTRIBUTION | - |
dc.subject.keywordPlus | GENERAL-POPULATION | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | MODEL | - |
dc.subject.keywordAuthor | hepatitis C virus | - |
dc.subject.keywordAuthor | infection | - |
dc.subject.keywordAuthor | Korea | - |
dc.subject.keywordAuthor | prevalence | - |
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